Evidence map›Paper›PMID 33400615›Full record

ArticleEmerging microbes & infections2021

Emergence and spread of novel H5N8, H5N5 and H5N1 clade 2.3.4.4 highly pathogenic avian influenza in 2020.

Nicola S Lewis, Ashley C Banyard, Elliot Whittard, Talgat Karibayev, Thamer Al Kafagi, Ilya Chvala, Alex Byrne, Saduakassova Meruyert Akberovna, Jacqueline King, Timm Harder and 12 more

Abstract readLetter
In one paragraph

Article in Emerging microbes & infections, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 167 papers.

0numbers the graph read from it
0cells of the map it votes in
167citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

167 citing papers in PubMed.

  1. Trial
  2. Counting cases, conserving species: addressing highly pathogenic avian influenza in wildlife.Biological reviews of the Cambridge Philosophical Society · 2026
    Review
  3. Article
  4. Influenza.Nature reviews. Disease primers · 2026
    Review
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  20. Article

107 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Nicola S LewisDepartment of Virology, Animal and Plant Health Agency, OIE/FAO International Reference Laboratory for Avian Influenza, Swine Influenza and Newcastle Disease Virus, Surrey, UK.
Ashley C BanyardDepartment of Virology, Animal and Plant Health Agency, OIE/FAO International Reference Laboratory for Avian Influenza, Swine Influenza and Newcastle Disease Virus, Surrey, UK.
Elliot WhittardDepartment of Virology, Animal and Plant Health Agency, OIE/FAO International Reference Laboratory for Avian Influenza, Swine Influenza and Newcastle Disease Virus, Surrey, UK.
Talgat KaribayevNational Veterinary Reference Centre, Infectious Diseases Laboratory, The Committee for Veterinary Control and Supervision, Nur-Sultan City, Republic of Kazakhstan.
Thamer Al KafagiVeterinary Directorate, Baghdad, Iraq.
Ilya ChvalaNational Reference Laboratory for Avian Influenza and Newcastle Disease, Federal Centre for Animal Health (FGBI "ARRIAH"), Yur'evets Vladimir, Russia.
Alex ByrneDepartment of Virology, Animal and Plant Health Agency, OIE/FAO International Reference Laboratory for Avian Influenza, Swine Influenza and Newcastle Disease Virus, Surrey, UK.
Saduakassova Meruyert AkberovnaDepartment of Virology, The Kazakh Scientific Research Veterinary Institute (KazSRVI), Non-Commercial JSC "National Agrarian Science and Educational Centre", Almaty, Republic of Kazakhstan.
Jacqueline KingInstitute of Diagnostic Virology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald-Insel Riems, Germany.
Timm HarderInstitute of Diagnostic Virology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald-Insel Riems, Germany.
Christian GrundInstitute of Diagnostic Virology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald-Insel Riems, Germany.
Steve EssenDepartment of Virology, Animal and Plant Health Agency, OIE/FAO International Reference Laboratory for Avian Influenza, Swine Influenza and Newcastle Disease Virus, Surrey, UK.
Scott M ReidDepartment of Virology, Animal and Plant Health Agency, OIE/FAO International Reference Laboratory for Avian Influenza, Swine Influenza and Newcastle Disease Virus, Surrey, UK.
Adam BrouwerDepartment of Virology, Animal and Plant Health Agency, OIE/FAO International Reference Laboratory for Avian Influenza, Swine Influenza and Newcastle Disease Virus, Surrey, UK.
Nikolay G ZinyakovNational Reference Laboratory for Avian Influenza and Newcastle Disease, Federal Centre for Animal Health (FGBI "ARRIAH"), Yur'evets Vladimir, Russia.
Azimkhan TegzhanovNational Veterinary Reference Centre, Infectious Diseases Laboratory, The Committee for Veterinary Control and Supervision, Nur-Sultan City, Republic of Kazakhstan.
Victor IrzaNational Reference Laboratory for Avian Influenza and Newcastle Disease, Federal Centre for Animal Health (FGBI "ARRIAH"), Yur'evets Vladimir, Russia.
Anne PohlmannInstitute of Diagnostic Virology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald-Insel Riems, Germany.ORCID https://orcid.org/0000-0002-5318-665X
Martin BeerInstitute of Diagnostic Virology, Friedrich-Loeffler-Institut, Federal Research Institute of Animal Health, Greifswald-Insel Riems, Germany.ORCID https://orcid.org/0000-0002-0598-5254
Ron A M FouchierErasmus MC Department of Viroscience, Rotterdam, Netherlands.
Sultanov Akhmetzhan AkievichDepartment of Virology, The Kazakh Scientific Research Veterinary Institute (KazSRVI), Non-Commercial JSC "National Agrarian Science and Educational Centre", Almaty, Republic of Kazakhstan.
Ian H BrownDepartment of Virology, Animal and Plant Health Agency, OIE/FAO International Reference Laboratory for Avian Influenza, Swine Influenza and Newcastle Disease Virus, Surrey, UK.

Funding

NIAID NIH HHS HHSN272201400008C
6 · The paper itself

Abstract

Analyses of HPAI H5 viruses from poultry outbreaks across a wide Eurasian region since July 2020 including the Russian Federation, Republics of Iraq and Kazakhstan, and recent detections in migratory waterfowl in the Netherlands, revealed undetected maintenance of H5N8, likely in galliform poultry since 2017/18 and both H5N5 and H5N1. All viruses belong to A/H5 clade 2.3.4.4b with closely related HA genes. Heterogeneity in Eurasian H5Nx HPAI emerging variants threatens poultry production, food security and veterinary public health.

Indexed as

AnimalsDisease OutbreaksInfluenza A virusInfluenza A Virus, H5N1 SubtypeInfluenza A Virus, H5N8 SubtypeInfluenza in BirdsIraqKazakhstanNetherlandsPhylogenyPoultryRussiaWhole Genome SequencingavianemergenceEurasiaHPAIInfluenza

Identifiers

PMID33400615
PMCPMC7832535

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.