Evidence map›Paper›PMID 33400338›Full record

ArticleTropical medicine & international health : TM & IH2020

Retinopathy in adults with hypertension and diabetes mellitus in Western Tanzania: a cross-sectional study.

Richmond Woodward, Evarista Mgaya, Christopher Mwanansao, Robert N Peck, Alan Wu, Grace Sun

Open access · greenAbstract read
In one paragraph

Article in Tropical medicine & international health : TM & IH, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 9 citations in OpenAlex.

  1. Pooled it
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  5. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Richmond WoodwardDepartment of Ophthalmology, Duke University, Durham, NC, USA.ORCID 0000-0003-1737-006X
Evarista MgayaDepartment of Ophthalmology, Bugando Medical Center, Mwanza, Tanzania.
Christopher MwanansaoDepartment of Ophthalmology, Bugando Medical Center, Mwanza, Tanzania.
Robert N PeckCenter for Global Health, Weill Cornell Medical College, New York, NY, USA.ORCID 0000-0002-4526-2480
Alan WuDivision of Biostatistics and Epidemiology, Department of Healthcare Policy & Research, Weill Cornell Medicine, New York, NY, USA.
Grace SunDepartment of Ophthalmology, Weill Cornell Medical College, New York, NY, USA.
Cornell University · USBugando Medical Centre · TZDuke University · US

Funding

Disparities in COVID Disease Severity and Outcomes in New York CityUL1TR002384 · NCATS · WEILL MEDICAL COLL OF CORNELL UNIV · PI JULIANNE L IMPERATO-MCGINLEY · 2017 to 2026
$86.2M
Hypertension in HIV-Infected Tanzanians: Time Course and PathogenesisK01TW010281 · FIC · WEILL MEDICAL COLL OF CORNELL UNIV · PI PECK, ROBERT N · 2015 to 2019
$689k
FIC NIH HHS K01 TW010281NCATS NIH HHS UL1 TR002384NIH HHS K01 TW010281Research to Prevent BlindnessWeill Cornell Medical College
6 · The paper itself

Abstract

objectiveLittle is known about the retinal manifestations of arterial hypertension (HTN) and diabetes mellitus (DM) in Western Tanzania and how to maximise the utilisation of scarce eye health resources. To address this, we determined the prevalence of hypertensive and diabetic retinopathy (DR), associated risk factors and relevant patient knowledge.

methodsAdults with HTN or DM attending outpatient clinics at Bugando Medical Center (BMC) from June to August 2017 were enrolled. Fundus photographs were obtained, and data were collected on blood pressure (BP), body mass index (BMI), blood sugar, visual acuity (VA) and responses to questions about the effects of HTN and DM on the eye.

resultsA total of 180 persons were screened. When only individuals with DR were considered, bivariate regression found systolic BP was significantly associated with severity of DR (P = 0.034). Receiver operating characteristic (ROC) curve analysis using the maximum Youden index revealed the optimum cut-off using duration of DM to predict any DR was 8 years (AUC = 0.75, 95% CI 0.65-0.85). Fewer persons with HTN were aware of the effect of high BP on the eye (61.6%) than persons with DM who were aware of the effect of high blood sugar on the eye (74.4%) (P = 0.048).

conclusionEfforts should be made to vigorously treat HTN among adults with DM and refer adults with duration of DM of 8 years or more for a dilated retinal examination. Additional efforts should be made to promote awareness of the sight threatening potential of HTN in resource-limited settings.

Indexed as

Diabetes Mellitus, Type 2Health Knowledge, Attitudes, PracticeHypertensionAdultAgedCross-Sectional StudiesDiabetic RetinopathyFemaleHumansMaleMedically Underserved AreaMiddle AgedRisk FactorsTanzaniaYoung AdultAfricaAfriquedépistagediabetic retinopathyhypertensive retinopathyprevalenceprévalencerétinopathie diabétiquerétinopathie hypertensivescreeningTanzaniaTanzanie

Identifiers

PMID33400338
PMCPMC7785861
OpenAlexW3043448460

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.