Evidence map›Paper›PMID 33400303›Full record

SynthesisAnnals of the New York Academy of Sciences2021

Interventions to increase adherence to micronutrient supplementation during pregnancy: a systematic review.

Filomena Gomes, Shannon E King, Diana Dallmann, Jenna Golan, Ana Carolina Feldenheimer da Silva, Kristen M Hurley, Gilles Bergeron, Megan W Bourassa, Saurabh Mehta

Open access · hybridAbstract readSystematic Review
In one paragraph

Synthesis in Annals of the New York Academy of Sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 4 pooled it
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 4 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
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  7. Artificial intelligence for personalized multiple micronutrient supplementation in maternal health.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026
    Review
  8. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Filomena GomesThe New York Academy of Sciences, New York City, New York.ORCID 0000-0003-1702-1433
Shannon E KingHuman Nutrition, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.ORCID 0000-0001-9709-3562
Diana DallmannSchool of Human Nutrition, McGill University, Montreal, Quebec, Canada.ORCID 0000-0001-7462-579X
Jenna GolanDivision of Nutritional Sciences, Cornell University, Ithaca, New York.ORCID 0000-0002-2249-7084
Ana Carolina Feldenheimer da SilvaDepartment of Nutrition in Public Health, University of State of Rio de Janeiro, Rio de Janeiro, Brazil.ORCID 0000-0001-5554-8856
Kristen M HurleyHuman Nutrition, Johns Hopkins Bloomberg School of Public Health, Baltimore, Maryland.
Gilles BergeronThe New York Academy of Sciences, New York City, New York.
Megan W BourassaThe New York Academy of Sciences, New York City, New York.
Saurabh MehtaDivision of Nutritional Sciences, Cornell University, Ithaca, New York.ORCID 0000-0003-3788-0665
New York Academy of Sciences · USCornell University · USJohns Hopkins University · USMcGill University · CAUniversidade do Estado do Rio de Janeiro · BR

Funding

NUTRITION TRAININGT32DK007158 · NIDDK · CORNELL UNIVERSITY ITHACA · PI PATRICIA A CASSANO, Julia L. Finkelstein · 1986 to 2026
$7.4M
NIDDK NIH HHS T32 DK007158
6 · The paper itself

Abstract

Prenatal micronutrient supplements are cost-effective in reducing nutritional deficiencies and adverse pregnancy and birth outcomes. However, poor adherence remains a potential barrier to the successful implementation of these supplementation programs. This systematic review assessed the effectiveness of interventions designed to increase adherence to prenatal micronutrient supplementation. Following the Cochrane Collaboration Methodology, literature searches were conducted in six electronic databases and gray literature (on July 24, 2020), and abstract screening, data extraction, and risk of bias assessment were conducted independently by two reviewers. We included 22 studies. Interventions that resulted in increased adherence were most of the education-based strategies, consumption monitoring by volunteer health workers or family members, SMS reminders, free provision of supplements, a multicomponent intervention with community mobilization, and a participatory action research intervention. In several studies, increased adherence was accompanied by beneficial effects on pregnancy and birth outcomes. Given the heterogeneity of study designs and methods used to define and measure adherence, a meta-analysis was not appropriate. We identified several potentially effective strategies to improve supplementation adherence, which may need to be adapted to specific contexts when considered for program implementation. However, additional high-quality studies are critically needed to effectively guide policies and programs.

Indexed as

Dietary SupplementsPatient ComplianceFemaleHumansMicronutrientsOutcome Assessment, Health CarePregnancyPrenatal CarePrenatal EducationPrenatal Nutritional Physiological PhenomenaMicronutrientsadherencecompliancemicronutrientspregnancysupplementation

Identifiers

PMID33400303
PMCPMC8169578
OpenAlexW3119072689

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.