ArticleMagnetic resonance in medicine2021
Using 5D flow MRI to decode the effects of rhythm on left atrial 3D flow dynamics in patients with atrial fibrillation.
Article in Magnetic resonance in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 27 citations in OpenAlex.
- Generative MR Multitasking With Complex-Harmonic Cardiac Encoding: Bridging the Gap Between Gated Imaging and Real-Time Imaging.Magnetic resonance in medicine · 2026Article
- Free-Breathing Dynamic, Regularized, Adaptive Cluster Optimization (DRACO) Cine Cardiac MRI in Atrial Fibrillation.Journal of magnetic resonance imaging : JMRI · 2026Article
- Role of imaging techniques in monitoring atrial cardiomyopathy and atrial failure: a scientific statement.ESC heart failure · 2026Review
- Automated adaptive detection and reconstruction of quiescent cardiac phases in free-running whole-heart acquisitions using Synchronicity Maps from PHysiological mOtioN In Cine (SYMPHONIC) MRI.Magma (New York, N.Y.) · 2026Article
- Third trimester fetal 4D flow MRI with motion correction.Magnetic resonance in medicine · 2025Article
- Self-gated free-running 5D whole-heart MRI using blind source separation for automated cardiac motion extraction.Magnetic resonance in medicine · 2025Article
- High on sparsity: Interbin compensation of cardiac motion for improved assessment of left-ventricular function using 5D whole-heart MRI.Magnetic resonance in medicine · 2025Article
- Free-Running Cardiac and Respiratory Motion-Resolved Imaging: A Paradigm Shift for Managing Motion in Cardiac MRI?Diagnostics (Basel, Switzerland) · 2024Review
- Robust and fast stochastic 4D flow vector-field signature technique for quantifying composite flow dynamics from 4D flow MRI: Application to left atrial flow in atrial fibrillation.Medical image analysis · 2024Article
- The future of cardiovascular magnetic resonance: All-in-one vs. real-time (Part 1).Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2024Review
- 4D Flow cardiovascular magnetic resonance consensus statement: 2023 update.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2023Review
- Atrial cardiomyopathy: Current and future imaging methods for assessment of atrial structure and function.Frontiers in cardiovascular medicine · 2023Review
- Left atrium 4D-flow segmentation with high-resolution contrast-enhanced magnetic resonance angiography.Frontiers in cardiovascular medicine · 2023Article
- Motion-compensated TFrontiers in cardiovascular medicine · 2023Review
- 4D Flow MR Imaging of the Left Atrium: What is Non-physiological Blood Flow in the Cardiac System?Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine · 2022Article
- Baseline 4D Flow-DerivedFrontiers in cardiovascular medicine · 2022Article
- Simultaneous multi-parametric acquisition and reconstruction techniques in cardiac magnetic resonance imaging: Basic concepts and status of clinical development.Frontiers in cardiovascular medicine · 2022Review
- Left atrial evaluation by cardiovascular magnetic resonance: sensitive and unique biomarkers.European heart journal. Cardiovascular Imaging · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 4 institutions in 2 countries.
Funding
Abstract
purposeThis study used a 5D flow framework to explore the influence of arrhythmia on thrombogenic hemodynamic parameters in patients with atrial fibrillation (AF).
methodsA fully self-gated, 3D radial, highly accelerated free-running 5D flow sequence with interleaved four-point velocity-encoding was acquired using an in vitro arrhythmic flow phantom and in 25 patients with a history of AF (68 ± 8 y, 6 female). Self-gating signals were used to calculate AF burden, bin data, and tag each k-space line with its RR
resultsIn vitro results demonstrated successful recovery of RR-binned flow curves using RR-resolved 5D flow compared to a real-time PC reference standard. In vivo, 5D flow was acquired in 8:48 minutes. AF burden was significantly correlated with 5D flow-derived peak (PV) and mean (MV) velocity and stasis (|ρ| = 0.54-0.75, P < .001). Sensitivity analyses determined a threshold for low versus high AF burden at 9.7%. High burden patients had increased LA mean stasis (up to +42%, P < .01), and lower MV and PV (-30%, -40.6%, respectively, P < .01). RR4 deviated furthest from respiratory-resolved reconstruction (end-expiration) with increased mean stasis (7.6% ± 14.0%, P = .10) and decreased PV (-12.7 ± 14.2%, P = .09).
conclusionsRR-resolved 5D flow can capture temporal and RR-resolved 3D hemodynamics in <10 minutes and offers a novel approach to investigate arrhythmias.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.