Observational studyClinical research in cardiology : official journal of the German Cardiac Society2021
Energy intake during hospital stay predicts all-cause mortality after discharge independently of nutritional status in elderly heart failure patients.
Observational study in Clinical research in cardiology : official journal of the German Cardiac Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.
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Who cites it
25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 37 citations in OpenAlex.
- Natriuretic peptides and C-reactive protein in in heart failure and malnutrition: a systematic review and meta-analysis.ESC heart failure · 2024Pooled it
- Therapeutic Fasting in Reducing Chemotherapy Side Effects in Cancer Patients: A Systematic Review and Meta-Analysis.Nutrients · 2023Pooled it
- Malnutrition and Cachexia in Inpatients With Acute Cardiac Conditions: A Scientific Statement From the American Heart Association.Circulation · 2026Review
- Association of Cachexia with Activities of Daily Living and Discharge Destinations among Inpatients with Dysphagia undergoing Convalescent Rehabilitation: A Multicenter Cohort Study.Annals of geriatric medicine and research · 2026Article
- Loop Diuretic Dose and Nutritional Status of Patients with Heart Failure with Reduced Ejection Fraction.Nutrients · 2025Article
- Pre-discharge energy intake and post-discharge mortality in acutely hospitalized older adults.Aging clinical and experimental research · 2025Article
- Clinical Importance of Protein Intake in Hospitalized Elderly Patients With Heart Failure.Circulation reports · 2025Article
- Correlation Between Prognostic Nutritional Index and Heart Failure in Adults with Diabetes in the United States: Study Results from NHANES (1999-2016).Reviews in cardiovascular medicine · 2025Article
- Associations between Physical Activity, Systemic Inflammation, and Hospital Admissions in Adults with Heart Failure.Cardiopulmonary physical therapy journal · 2024Article
- Associations between in-hospital daily protein intake and adverse clinical outcomes in older patients with heart failure.ESC heart failure · 2024Article
- The treatment of chronic anemia in heart failure: a global approach.Clinical research in cardiology : official journal of the German Cardiac Society · 2024Review
- Relationship between serum iron level and physical function in heart failure patients is lost by presence of diabetes.ESC heart failure · 2024Article
- Circulating level of β-aminoisobutyric acid (BAIBA), a novel myokine-like molecule, is inversely associated with fat mass in patients with heart failure.Heart and vessels · 2024Article
- Independent Association Between Use of Proton Pump Inhibitors and Muscle Wasting in Patients with Heart Failure: A Single-Center, Ambispective, Observational Study.Drugs & aging · 2023Observational
- Are Energy and Protein Intakes Lower Than Requirements in Older Adults? An Urgent Issue in Hospitals and Nursing Homes.Nutrients · 2023Article
- Impact of Radar Chart-Based Information Sharing in a Multidisciplinary Team on In-Hospital Outcomes and Prognosis in Older Patients With Heart Failure.Circulation reports · 2023Article
- Resting Energy Expenditure in Older Inpatients: A Comparison of Prediction Equations and Measurements.Nutrients · 2022Article
- Nonpharmacological Strategies in Heart Failure with Preserved Ejection Fraction.Cardiology clinics · 2022Review
- Delayed dexamethasone treatment at initiation of oxygen supplementation for coronavirus disease 2019 is associated with the exacerbation of clinical condition.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2022Article
- Mortality risks of body mass index and energy intake trajectories in institutionalized elderly people: a retrospective cohort study.BMC geriatrics · 2022Article
Corrections and comments
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Authors and funding
19 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveMalnutrition is associated with an increased risk of mortality in heart failure (HF) patients. Here, we examined the hypothesis that assessment of energy intake in addition to nutritional status improves the stratification of mortality risk in elderly HF patients.
methodsWe retrospectively examined 419 HF patients aged ≥ 65 years (median 78 years, 49% female). Nutritional status was assessed by the Mini Nutritional Assessment Short Form (MNA-SF), and daily energy intake was calculated from intake during 3 consecutive days before discharge.
resultsDuring a median 1.52-year period (IQR 0.96-2.94 years), 110 patients (26%) died. Kaplan-Meier survival curves showed that patients with low tertile of daily energy intake had a higher mortality rate than did patients with high or middle tertile of daily energy intake. In multivariate Cox regression analyses, low daily energy intake was independently associated with higher mortality after adjustment for the model including age, sex, BNP, Charlson Comorbidity Index, history of HF hospitalization, and cachexia in addition to MNA-SF. Inclusion of both MNA-SF and energy intake into the adjustment model improved the accuracy of prediction of the mortality after discharge (continuous net reclassification improvement, 0.355, p = 0.003; integrated discrimination improvement, 0.029, p = 0.003). Results of a fully adjusted dose-dependent association analysis showed that risk of all-cause mortality was lowest among HF patients who consumed 31.5 kcal/kg/day of energy.
conclusionsEnergy intake during hospital stay is an independent predictor of the mortality in elderly HF patients, and its assessment together with established predictors improves the mortality risk stratification.
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