ArticleThe EMBO journal2021
Modulation of plant root growth by nitrogen source-defined regulation of polar auxin transport.
Article in The EMBO journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 1 of them a synthesis that pooled it.
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Who cites it
47 citing papers in PubMed, 1 synthesis or guideline pooled it, 98 citations in OpenAlex.
- A multiscale growth atlas of Arabidopsis: linking cell dynamics to organ development.The New phytologist · 2026Pooled it
- Quantitative Measurement of Basipetal Auxin Transport in Arabidopsis Roots ViaMethods in molecular biology (Clifton, N.J.) · 2027Article
- Nitrogen sources modulate auxin transport to fine-tune root system architecture.Plant cell reports · 2026Article
- Targeting redundant gene families: A multiplexed, tissue-specific CRISPR toolbox for Arabidopsis genetic screens.Cell reports · 2026Article
- The transcription factor OsMADS61 positively regulates root elongation and nitrogen use efficiency in rice.Plant communications · 2026Article
- Soybean Auxin Transporter PIN3 Regulates Nitrate Acquisition to Improve Nitrogen Use and Seed Traits.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Hyperspectral imaging of grains uncovers the genetic architecture of nitrogen response of development in bread wheat.Molecular breeding : new strategies in plant improvement · 2025Article
- Light intensity and sulfur deficiency modulate growth and water dynamics in broccoli plants via aquaporin regulation.Plant biology (Stuttgart, Germany) · 2025Article
- Computational modeling of plant root development: the art and the science.The New phytologist · 2025Review
- Mining the Candidate Transcription Factors Modulating Tanshinones' and Phenolic Acids' Biosynthesis Under Low Nitrogen Stress inInternational journal of molecular sciences · 2025Article
- Genome-Wide Identification and Expression Analysis of PkNRT Gene Family in Korean Pine (Plants (Basel, Switzerland) · 2025Article
- Polarly localized Bro1 domain proteins regulate PIN-FORMED abundance and root gravitropic growth in Arabidopsis.Communications biology · 2024Article
- Circadian Rhythm and Nitrogen Metabolism Participate in the Response of Boron Deficiency in the Root ofInternational journal of molecular sciences · 2024Article
- Exogenous GAInternational journal of molecular sciences · 2024Article
- Nitrogen sensing and regulatory networks: it's about time and space.The Plant cell · 2024Review
- Ammonium treatment inhibits cell cycle activity and induces nuclei endopolyploidization in Arabidopsis thaliana.Planta · 2024Article
- Reproducible growth ofScience advances · 2024Article
- Plastid-localized amino acid metabolism coordinates rice ammonium tolerance and nitrogen use efficiency.Nature plants · 2023Article
- Plant nitrogen availability and crosstalk with phytohormones signallings and their biotechnology breeding application in crops.Plant biotechnology journal · 2023Review
- Article
Corrections and comments
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Authors and funding
18 authors at 5 institutions in 4 countries.
Funding
Abstract
Availability of the essential macronutrient nitrogen in soil plays a critical role in plant growth, development, and impacts agricultural productivity. Plants have evolved different strategies for sensing and responding to heterogeneous nitrogen distribution. Modulation of root system architecture, including primary root growth and branching, is among the most essential plant adaptions to ensure adequate nitrogen acquisition. However, the immediate molecular pathways coordinating the adjustment of root growth in response to distinct nitrogen sources, such as nitrate or ammonium, are poorly understood. Here, we show that growth as manifested by cell division and elongation is synchronized by coordinated auxin flux between two adjacent outer tissue layers of the root. This coordination is achieved by nitrate-dependent dephosphorylation of the PIN2 auxin efflux carrier at a previously uncharacterized phosphorylation site, leading to subsequent PIN2 lateralization and thereby regulating auxin flow between adjacent tissues. A dynamic computer model based on our experimental data successfully recapitulates experimental observations. Our study provides mechanistic insights broadening our understanding of root growth mechanisms in dynamic environments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.