Evidence map›Paper›PMID 33399002›Full record

ArticleHypertension (Dallas, Tex. : 1979)2021

Concerns on the Specificity of Commercial ELISAs for the Measurement of Angiotensin (1-7) and Angiotensin II in Human Plasma.

Mark C Chappell, Nancy T Pirro, Andrew M South, TanYa M Gwathmey

Open access · bronzeAbstract readEvaluation StudyLetter
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 1 pooled it
7.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
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  4. A pilot study to assess the circulating renin-angiotensin system in COVID-19 acute respiratory failure.American journal of physiology. Lung cellular and molecular physiology · 2021
    Trial
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  9. Alternative Renin-Angiotensin System.Hypertension (Dallas, Tex. : 1979) · 2024
    Review
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  11. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Mark C ChappellFrom the Hypertension and Vascular Research Center (M.C.C., N.T.P., A.M.S., T.M.G.), Wake Forest University School of Medicine, Winston-Salem, NC.
Nancy T PirroFrom the Hypertension and Vascular Research Center (M.C.C., N.T.P., A.M.S., T.M.G.), Wake Forest University School of Medicine, Winston-Salem, NC.
Andrew M SouthFrom the Hypertension and Vascular Research Center (M.C.C., N.T.P., A.M.S., T.M.G.), Wake Forest University School of Medicine, Winston-Salem, NC.
TanYa M GwathmeyFrom the Hypertension and Vascular Research Center (M.C.C., N.T.P., A.M.S., T.M.G.), Wake Forest University School of Medicine, Winston-Salem, NC.
Wake Forest University · US

Funding

Uric Acid, Klotho and Salt Sensitivity in Young Adults Born PretermR01HL146818 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI CHAPPELL, MARK C, SHALTOUT, HOSSAM · 2019 to 2023
$4.0M
The role of angiotensin-(1-7) in hypertension and hypertension-induced heart and kidney damageK23HL148394 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI SOUTH, ANDREW MICHAEL · 2020 to 2024
$783k
NHLBI NIH HHS K23 HL148394NHLBI NIH HHS L40 HL148910NHLBI NIH HHS R01 HL146818
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Enzyme-Linked Immunosorbent AssaySARS-CoV-2Angiotensin IAngiotensin IIChromatography, AgaroseCOVID-19HumansPeptide FragmentsRadioimmunoassayReference StandardsRenin-Angiotensin SystemSensitivity and SpecificitySpecimen HandlingAngiotensin Iangiotensin I (1-7)Angiotensin IIPeptide Fragmentscoronavirusheart failurekidney diseasespandemicsrenin-angiotensin system

Identifiers

PMID33399002
PMCPMC7878344
OpenAlexW3119327095

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.