Evidence map›Paper›PMID 33398853›Full record

SynthesisReproductive sciences (Thousand Oaks, Calif.)2021

The Associations of Genital Mycoplasmas with Female Infertility and Adverse Pregnancy Outcomes: a Systematic Review and Meta-analysis.

Caifeng Ma, Jikun Du, Yuhong Dou, Rui Chen, Yuxia Li, Lijun Zhao, Helu Liu, Kebin Zhang

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Reproductive sciences (Thousand Oaks, Calif.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 2 pooled it
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 2 syntheses or guidelines pooled it, 44 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Descriptive analysis of genital colonization across gestational trimesters in pregnant women with different obstetric histories.Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia · 2026
    Article
  5. Article
  6. Article
  7. BMJ open · 2025
    Article
  8. Cervicovaginal microbial features predictInfection and immunity · 2025
    Article
  9. Article
  10. Understanding the Associations of Urogenital Microbiomes With Fertility and In Vitro Fertilization.American journal of reproductive immunology (New York, N.Y. : 1989) · 2025
    Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Distribution of Macrolide Resistant Mycoplasma genitalium in Urogenital Tract Specimens From Women Enrolled in a US Clinical Study Cohort.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023
    Article
  16. Retrospective Analysis of Azithromycin-ResistantInfection and drug resistance · 2023
    Article
  17. Frontiers in microbiology · 2023
    Review
  18. Epidemiology and infection · 2022
    Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Caifeng MaClinical Medicine Research Center, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing, China.ORCID http://orcid.org/0000-0001-9965-2604
Jikun DuDepartment of Clinical Laboratory, Central Research Laboratory, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen Shajing Hospital affiliated to Guangzhou Medical University, Shenzhen, China.
Yuhong DouDepartment of Clinical Laboratory, Central Research Laboratory, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen Shajing Hospital affiliated to Guangzhou Medical University, Shenzhen, China.
Rui ChenDepartment of Clinical Laboratory, The Second People's Hospital of Futian District, Shenzhen, China.
Yuxia LiDepartment of Clinical Laboratory, Central Research Laboratory, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen Shajing Hospital affiliated to Guangzhou Medical University, Shenzhen, China.
Lijun ZhaoDepartment of Clinical Laboratory, Central Research Laboratory, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen Shajing Hospital affiliated to Guangzhou Medical University, Shenzhen, China.
Helu LiuDepartment of Clinical Laboratory, Central Research Laboratory, Shenzhen Hospital of Integrated Traditional Chinese and Western Medicine, Shenzhen Shajing Hospital affiliated to Guangzhou Medical University, Shenzhen, China. liuhelu@21cn.com.ORCID https://orcid.org/0000-0002-5584-533X
Kebin ZhangClinical Medicine Research Center, Xinqiao Hospital, Army Medical University (Third Military Medical University), Chongqing, China. zhangkebin12@163.com.ORCID https://orcid.org/0000-0003-2349-1167
Shenzhen Shajing Affiliated Hospital of Guangzhou Medical University · CNArmy Medical University · CNShenzhen Second People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The roles of genital mycoplasmas including Mycoplasma genitalium (M. genitalium), Mycoplasma hominis (M. hominis), Ureaplasma urealyticum (U. urealyticum), and Ureaplasma parvum (U. parvum) in reproductive diseases are equivocal. To investigate whether genital mycoplasmas are risk factors of female infertility and adverse pregnancy outcomes, we performed a systematic review and meta-analysis. Electronic databases were searched for related studies. A random-effects model or fixed-effects model was employed to generate forest plots. Pooled odd ratios (ORs) with 95% confidence intervals (CIs) were applied to measure the strength of associations. Meanwhile, heterogeneity was evaluated by H statistic and I

Indexed as

Abortion, SpontaneousCross-Sectional StudiesFemaleHumansInfertility, FemaleMycoplasma genitaliumMycoplasma hominisMycoplasma InfectionsObservational Studies as TopicPregnancyPregnancy OutcomePremature BirthStillbirthUreaplasmaUreaplasma InfectionsAdverse pregnancy outcomesFemaleGenital mycoplasmasInfertilityMeta-analysisSystematic review

Identifiers

PMID33398853
OpenAlexW3119454163

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.