Evidence map›Paper›PMID 33398789›Full record

ReviewJournal of muscle research and cell motility2021

The role of AMPK in regulation of Na

Sergej Pirkmajer, Metka Petrič, Alexander V Chibalin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Journal of muscle research and cell motility, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Phosphorylation of NaThe Journal of membrane biology · 2021
    Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Sergej PirkmajerFaculty of Medicine, Institute of Pathophysiology, University of Ljubljana, Ljubljana, Slovenia. sergej.pirkmajer@mf.uni-lj.si.ORCID 0000-0003-1459-6936
Metka PetričFaculty of Medicine, Institute of Pathophysiology, University of Ljubljana, Ljubljana, Slovenia.ORCID 0000-0001-9483-242X
Alexander V ChibalinDepartment of Molecular Medicine and Surgery, Integrative Physiology, Karolinska Institutet, Stockholm, Sweden. alexander.chibalin@ki.se.ORCID 0000-0002-6339-6271
University of Ljubljana · SINational Research Tomsk State University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

AMP-activated protein kinase (AMPK) is a cellular energy gauge and a major regulator of cellular energy homeostasis. Once activated, AMPK stimulates nutrient uptake and the ATP-producing catabolic pathways, while it suppresses the ATP-consuming anabolic pathways, thus helping to maintain the cellular energy balance under energy-deprived conditions. As much as ~ 20-25% of the whole-body ATP consumption occurs due to a reaction catalysed by Na

Indexed as

Adenosine TriphosphatasesAMP-Activated Protein KinasesHumansIonsMuscle, SkeletalAdenosine TriphosphatasesAMP-Activated Protein KinasesIonsAMPKEnergy metabolismNa+, K+-ATPaseSkeletal muscle

Identifiers

PMID33398789
OpenAlexW3120169133

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.