Evidence map›Paper›PMID 33398672›Full record

ArticleBrazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]2021

Streptococcus agalactiae strains isolated from cancer patients in Rio de Janeiro, Brazil.

Glenda de Figueiredo Sanches, Pamella Silva Lannes-Costa, Melissa Coimbra Cristoforêto, Kelly S Doran, Ana Luíza Mattos-Guaraldi, Prescilla Emy Nagao

Abstract read
In one paragraph

Article in Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology], 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Genomic characterization of group BMicrobial genomics · 2025
    Article
  4. Article
  5. Article
  6. Editorial:Frontiers in microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Glenda de Figueiredo SanchesLaboratório de Biologia Molecular e Fisiologia de Estreptococos, Instituto de Biologia Roberto Alcantara Gomes, Rio de Janeiro State University, Rua São Francisco Xavier, 524 - PHLC 5º andar sala 501B-Maracanã, Rio de Janeiro, RJ, CEP 20550-013, Brazil.ORCID https://orcid.org/0000-0002-9144-1826
Pamella Silva Lannes-CostaLaboratório de Biologia Molecular e Fisiologia de Estreptococos, Instituto de Biologia Roberto Alcantara Gomes, Rio de Janeiro State University, Rua São Francisco Xavier, 524 - PHLC 5º andar sala 501B-Maracanã, Rio de Janeiro, RJ, CEP 20550-013, Brazil.ORCID https://orcid.org/0000-0003-2728-8123
Melissa Coimbra CristoforêtoLaboratório de Biologia Molecular e Fisiologia de Estreptococos, Instituto de Biologia Roberto Alcantara Gomes, Rio de Janeiro State University, Rua São Francisco Xavier, 524 - PHLC 5º andar sala 501B-Maracanã, Rio de Janeiro, RJ, CEP 20550-013, Brazil.ORCID https://orcid.org/0000-0002-7869-4087
Kelly S DoranDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, CO, USA.ORCID https://orcid.org/0000-0003-4232-6837
Ana Luíza Mattos-GuaraldiFaculdade de Ciências Médicas, Rio de Janeiro State University (UERJ), Rio de Janeiro, RJ, Brazil.ORCID https://orcid.org/0000-0003-2522-0416
Prescilla Emy NagaoLaboratório de Biologia Molecular e Fisiologia de Estreptococos, Instituto de Biologia Roberto Alcantara Gomes, Rio de Janeiro State University, Rua São Francisco Xavier, 524 - PHLC 5º andar sala 501B-Maracanã, Rio de Janeiro, RJ, CEP 20550-013, Brazil. pnagao@uol.com.br.ORCID http://orcid.org/0000-0001-6007-0033

Funding

Blood-brain barrier in bacterial meningitisR01NS051247 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DORAN, KELLY S · 2006 to 2015
$3.2M
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior Finance Code 001Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/010.000895/2015NINDS NIH HHS NIH/NINDS R01-NS051247NINDS NIH HHS R01 NS051247Sub Reitoria de Pós-Graduação e Pesquisa da Universidade do Estado do Rio de Janeiro (SR-2/UERJ) postgraduate scholarships
6 · The paper itself

Abstract

Streptococcus agalactiae is a recognized pathogen associated with infections in neonates, elderly, and immunocompromised adults, particularly those with cancer. In the present investigation, clinical-epidemiological features, multidrug resistance profiles, and virulence genes of S. agalactiae strains isolated from cancer patients were investigated. S. agalactiae capsular distribution assays demonstrated that Ia (43.6%) and V (23.6%) types were predominantly detected among 55 clinical isolates tested; only one strain (GBS1428) was capsular type III/ST-17. The fbsB and hylB genes were detected in all isolates, while the iag, lmb, and fbsA genes were detected in 94.5%, 91%, and 91% of oncological isolates, respectively. The combination of PI-1 and PI-2a was the most common (60%) among S. agalactiae strains isolated from oncologic patients. S. agalactiae strains were resistant to tetracycline (85.5%), erythromycin (9%), and clindamycin (5.5%). Norfloxacin non-susceptible was detected in 7.3% of S. agalactiae strains. Our findings reinforce the need for S. agalactiae control measures in Brazil, including cancer patients.

Indexed as

AdolescentAdultAnti-Bacterial AgentsBacterial ProteinsBrazilDrug Resistance, Multiple, BacterialGenotypeHumansMicrobial Sensitivity TestsMiddle AgedNeoplasmsStreptococcal InfectionsStreptococcus agalactiaeVirulence FactorsYoung AdultAnti-Bacterial AgentsBacterial ProteinsVirulence FactorsAdultsAntimicrobial susceptibilityCancerSerotypesStreptococcus agalactiaeVirulence factors

Identifiers

PMID33398672
PMCPMC7966615

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.