Evidence map›Paper›PMID 33398637›Full record

ArticlePhysical and engineering sciences in medicine2021

Shell properties and concentration stability of acoustofluidic delivery agents.

Hussain Alsadiq, Karnaker Tupally, Robert Vogel, Ganesh Kokil, Harendra S Parekh, Martin Veidt

Abstract read
PubMed Publisher
In one paragraph

Article in Physical and engineering sciences in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Hussain AlsadiqSchool of Mechanical and Mining Engineering, University of Queensland, Brisbane, Australia. h.alsadiq@uq.edu.au.ORCID http://orcid.org/0000-0003-2826-4510
Karnaker TupallySchool of Pharmacy, University of Queensland, Brisbane, Australia.
Robert VogelSchool of Mathematics and Physics, University of Queensland, Brisbane, Australia.
Ganesh KokilSchool of Pharmacy, University of Queensland, Brisbane, Australia.
Harendra S ParekhSchool of Pharmacy, University of Queensland, Brisbane, Australia.
Martin VeidtSchool of Mechanical and Mining Engineering, University of Queensland, Brisbane, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper investigates the shell elastic properties and the number-concentration stability of a new acoustofluidic delivery agent liposome in comparison to Definity™, a monolayer ultrasonic contrast agent microbubble. The frequency dependent attenuation of an acoustic beam passing through a microbubble suspension was measured to estimate the shell parameters. The excitation voltage was adjusted to ensure constant acoustic pressure at all frequencies. The pressure was kept at the lowest possible magnitude to ensure that effects from nonlinear bubble behaviour which are not considered in the analytical model were minimal. The acoustofluidic delivery agent shell stiffness S

Indexed as

MicrobubblesUltrasonicsAcousticsContrast MediaUltrasonographyContrast MediaAcoustic attenuationAcoustofluidicsLiposomeUltrasound contrast agent

Identifiers

PMID33398637

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.