Evidence map›Paper›PMID 33398586›Full record

ArticleSurgical endoscopy2021

Endoscopic and percutaneous biliary interventions in patients with altered upper gastrointestinal anatomy-the Munich Multicenter Experience.

Simon Nennstiel, Kathrin Freivogel, Alexander Faber, Christoph Schlag, Bernhard Haller, Martin Blöchinger, Markus Dollhopf, Björn Lewerenz, Wolfgang Schepp, Jörg Schirra and 2 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Endoscopic Biliary Drainage in Surgically Altered Anatomy.Diagnostics (Basel, Switzerland) · 2023
    Review
  8. Article
  9. [Endoscopic retrograde cholangiopancreatography in patients after bilioenteric anstomosis].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2022
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 1 country.

Simon NennstielMedizinische Klinik und Poliklinik Für Innere Medizin II, Klinikum Rechts der Isar der TU München, Ismaninger Str. 22, 81675, Munich, Germany. simon.nennstiel@mri.tum.de.ORCID 0000-0001-8099-1251
Kathrin FreivogelInnere Medizin I, Krankenhaus Barmherzige Brüder München, Romanstraße 93, 80639, Munich, Germany.
Alexander FaberMedizinische Klinik und Poliklinik Für Innere Medizin II, Klinikum Rechts der Isar der TU München, Ismaninger Str. 22, 81675, Munich, Germany.
Christoph SchlagMedizinische Klinik und Poliklinik Für Innere Medizin II, Klinikum Rechts der Isar der TU München, Ismaninger Str. 22, 81675, Munich, Germany.
Bernhard HallerInstitut für Medizinische Informatik, Statistik und Epidemiologie, Klinikum Rechts der Isar der Technischen Universität München, Ismaninger Straße 22, 81675, Munich, Germany.
Martin BlöchingerKlinik für Gastroenterologie und Hepatologie, München Klinik Neuperlach (München Klinik gGmbH), Oskar-Maria-Graf-Ring 51, 81737, Munich, Germany.
Markus DollhopfKlinik für Gastroenterologie und Hepatologie, München Klinik Neuperlach (München Klinik gGmbH), Oskar-Maria-Graf-Ring 51, 81737, Munich, Germany.
Björn LewerenzKlinik für Gastroenterologie, Hepatologie und Gastroenterologische Onkologie, München Klinik Bogenhausen (München Klinik gGmbH), Englschalkinger Straße 77, 81925, Munich, Germany.
Wolfgang ScheppKlinik für Gastroenterologie, Hepatologie und Gastroenterologische Onkologie, München Klinik Bogenhausen (München Klinik gGmbH), Englschalkinger Straße 77, 81925, Munich, Germany.
Jörg SchirraMedizinische Klinik und Poliklinik 2, Klinikum der Universität München Standort Großhadern, Marchioninistraße 15, 81377, Munich, Germany.
Roland M SchmidMedizinische Klinik und Poliklinik Für Innere Medizin II, Klinikum Rechts der Isar der TU München, Ismaninger Str. 22, 81675, Munich, Germany.
Bruno NeuMedizinische Klinik II, Krankenhaus Landshut-Achdorf, Akademisches Lehrkrankenhaus der TU München, Achdorferweg 3, 84036, Landshut, Germany.
München Klinik Bogenhausen · DEMünchen Klinik Neuperlach · DETUM Klinikum · DEKrankenhaus Barmherzige Brüder · DELMU Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn patients with altered upper gastrointestinal anatomy, conventional endoscopic retrograde cholangiography is often not possible and different techniques, like enteroscopy-assisted or percutaneous approaches are required. Aim of this study was to analyze success and complication rates of these techniques in a large collective of patients in the daily clinical practice in a pre-endosonographic biliary drainage era. PATIENTS AND

methodsPatients with altered upper gastrointestinal anatomy with biliary interventions between March 1st, 2006, and June 30th, 2014 in four tertiary endoscopic centers in Munich, Germany were retrospectively analyzed.

resultsAt least one endoscopic-assisted biliary intervention was successful in 234/411 patients (56.9%)-in 192 patients in the first, in 34 patients in the second and in 8 patients in the third attempt. Success rates for Billroth-II/Whipple-/Roux-en-Y reconstruction were 70.5%/56.7%/49.5%. Complication rates for these reconstructions were 9.3%/6.5%/6.3%, the overall complication rate was 7.1%. Success rates were highest in patients with Billroth-II reconstruction where use of a duodenoscope was possible, complication rates were also highest in this scenario. Success rates were lowest in longer-limb anatomy like Roux-en-Y reconstruction. Percutaneous biliary drainages (PTBD) were inserted 268 times with substantially higher success (90.7%) as well as complication rates (11.6%) compared to the endoscopic approach. Compared to patients treated endoscopically, patients with PTBD had a lower performance status, more severe cholestasis and a significant higher rate of malignant underlying disease.

conclusionIn patients with altered upper gastrointestinal anatomy, success rates of endoscopic-assisted biliary interventions are lower compared to PTBD. Still, due to the beneficial complication rates of the endoscopic approach, this technique should be preferred whenever possible and in selected patients who still need to be defined in detail, repeated endoscopic attempts are useful to help achieve the desired result.

Indexed as

Cholangiopancreatography, Endoscopic RetrogradeCholestasisAnastomosis, Roux-en-YEndosonographyHumansRetrospective StudiesBiliary diseaseCholestasisEnteroscopy-assistedERCPPTBDSurgically altered anatomy

Identifiers

PMID33398586
OpenAlexW3120564429

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.