ArticleSurgical endoscopy2021
Inter-user variation in the interpretation of near infrared perfusion imaging using indocyanine green in colorectal surgery.
Article in Surgical endoscopy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 4 syntheses or guidelines pooled it, 56 citations in OpenAlex.
- Quantification of indocyanine green fluorescence angiography in colorectal surgery: a systematic review of the literature.Surgical endoscopy · 2025Pooled it
- Impact of indocyanine green fluorescence angiography on surgeon action and anastomotic leak in colorectal resections. A systematic review and meta-analysis.Surgical endoscopy · 2025Pooled it
- The impact of indocyanine green fluorescence angiography (ICG-FA) on anastomotic leak rates and postoperative outcomes in colorectal anastomoses: a systematic review.Surgical endoscopy · 2025Pooled it
- Indocyanine Green Fluorescence Using in Conduit Reconstruction for Patients With Esophageal Cancer to Improve Short-Term Clinical Outcome: A Meta-Analysis.Frontiers in oncology · 2022Pooled it
- Real-time intraoperative perfusion assessment using indocyanine green fluorescence angiography as a predictor of anastomotic integrity in colorectal surgery: A systematic review and meta-analysis.Surgery open science · 2026Article
- Assessment of intra-operative bowel perfusion in children using indocyanine green: an exploratory study investigating its effect on surgical management.Pediatric surgery international · 2026Article
- Improved Quantification of ICG Perfusion Through Motion Compensation in Fluorescence-Guided Surgery.Diagnostics (Basel, Switzerland) · 2026Article
- The evaluation of cognitive workload associated with indocyanine green fluorescence angiography in colorectal surgery.Surgical endoscopy · 2026Article
- Beyond fluorescence intensity: a Minimum acquisition and reporting standard and emerging technologies for colorectal indocyanine green fluorescence angiography studies.Frontiers in surgery · 2026Article
- AUGUR-AI: a real-time artificial intelligence interpreter for indocyanine green fluorescence angiography in colorectal surgery.Surgical endoscopy · 2025Article
- Quantitative blood perfusion assessment by the SPY-QP software program for minimally invasive rectal cancer surgery.Surgical endoscopy · 2025Article
- Quantitative intra-arterial fluorescence angiography for direct monitoring of peripheral revascularization effects.Journal of vascular surgery cases and innovative techniques · 2025Article
- AUGUR-AIM: Clinical validation of an artificial intelligence indocyanine green fluorescence angiography expert representer.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025Observational
- Colorectal surgeons' perspectives on the efficacy of intraoperative bowel perfusion technology with a focus on indocyanine green fluorescence angiography.Langenbeck's archives of surgery · 2025Article
- A novel flexible near-infrared endoscopic device that enables real-time artificial intelligence fluorescence tissue characterization.PloS one · 2025Article
- Dye-less quantification of tissue perfusion by laser speckle contrast imaging is equivalent to quantified indocyanine green in a porcine model.Surgical endoscopy · 2024Article
- Parathyroid gland identification and angiography classification using simple machine learning methods.BJS open · 2024Article
- Advancing indocyanine green fluorescence flap perfusion assessment via near infrared signal quantification.JPRAS open · 2024Article
- Near-infrared indocyanine green angiography in recognizing bowel ischemia in emergency surgery: game changer or overrated?Innovative surgical sciences · 2024Review
- Intraoperative near infrared functional imaging of rectal cancer using artificial intelligence methods - now and near future state of the art.European journal of nuclear medicine and molecular imaging · 2024Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionDespite increasing endorsement of near-infrared perfusion assessment using indocyanine green (ICG) during colorectal surgery, little work has yet been done regarding learning curve and interobserver variation most especially on surgical video reflective of real-world usage.
methodsSurgeons with established expertise in ICG usage were invited to participate in the study along with others without such experience including trainees. All participants completed an opinion questionnaire and interpreted video presentations of fluorescence angiograms in a variety of colorectal case scenarios. An interactive video platform (Mindstamp) enabled dynamic annotation. Statistical analysis of data was performed using Kruskal-Wallis and Mann-Whitney testing as well as Intraclass Correlation Coefficients and Fleiss Multi-rater Kappa Scoring.
resultsForty participants (six experts) completed questionnaire data and provided judgement of 14 videos (nine showing proximal colonic transection site perfusion, four showing completed anastomoses and one an acutely strangulated bowel). 70% felt > 10 cases were needed for competency in use with the majority of experts advocating > 50 (p < 0.05). Overall agreement among experts was "good" for videos showing colonic transection perfusion (versus "moderate" among in-experts) with experts clustering more distally. In contrast, there was no interpretation concordance among experts or in-experts when judging ICG perfusion sufficiency on a yes/no basis.
conclusionSignificant experience is recommended before reliance on ICG perfusion angiograms. ICG fluorescence assessment is prone to variable interpretation and influenced by experience and, perhaps, knowledge of preassessment operative steps suggesting a role for objective flow analysis with artificial intelligence methods as the next phase of this technology.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.