Evidence map›Paper›PMID 33398497›Full record

ArticleSocial psychiatry and psychiatric epidemiology2022

Dysfunctional family functioning in high socioeconomic status families as a risk factor for the development of psychiatric disorders in adoptees: the Finnish Adoptive Family Study of Schizophrenia.

Toni Myllyaho, Virva Siira, Karl-Erik Wahlberg, Helinä Hakko, Ville Tikkanen, Kristian Läksy, Riikka Roisko, Mika Niemelä, Sami Räsänen

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Article in Social psychiatry and psychiatric epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Toni MyllyahoUniversity of Oulu, Unit of Clinical Neuroscience, Psychiatry, University of Oulu, P.O. Box 5000, 90014, Oulu, Finland. toni.myllyaho@student.oulu.fi.ORCID http://orcid.org/0000-0001-5203-3339
Virva SiiraFaculty of Education, University of Oulu, P.O. Box 2000, 90014, Oulu, Finland.
Karl-Erik WahlbergUniversity of Oulu, Unit of Clinical Neuroscience, Psychiatry, University of Oulu, P.O. Box 5000, 90014, Oulu, Finland.
Helinä HakkoDepartment of Psychiatry, Oulu University Hospital, P.O. Box 26, 90014, Oulu, Finland.
Ville TikkanenUniversity of Oulu, Unit of Clinical Neuroscience, Psychiatry, University of Oulu, P.O. Box 5000, 90014, Oulu, Finland.
Kristian LäksySocial Security Institute of Finland (SSI), Helsinki, Finland.
Riikka RoiskoDepartment of Psychiatry, Oulu University Hospital, P.O. Box 26, 90014, Oulu, Finland.
Mika NiemeläDepartment of Psychiatry, Oulu University Hospital, P.O. Box 26, 90014, Oulu, Finland.
Sami RäsänenDepartment of Psychiatry, Oulu University Hospital, P.O. Box 26, 90014, Oulu, Finland.
Oulu University Hospital · FIUniversity of Oulu · FISocial Insurance Institution · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeEarlier findings indicate that socioeconomic status (SES) of family associates with family functioning. This study examined the impacts of family functioning and genetic risk for schizophrenia on psychiatric morbidity of adoptees in families of high SES (HSES) and low SES (LSES).

methodsThe study population is a subgroup of the Finnish Adoptive Family Study of Schizophrenia. Of the adoptees, 152 had high genetic risk for schizophrenia spectrum disorders (HR) and 151 adoptees had low risk (LR). Of the adoptees, 185 (HR = 94, LR = 91) were raised in high-SES (HSES) families and 118 (HR = 58, LR = 60) in low-SES (LSES) families. The family SES was determined by the occupational status of the main provider of the family. The functioning of adoptive families was assessed based on Global Family Ratings (GFRs) and psychiatric disorders on DSM-III-R criteria.

resultsIn the HSES families, the psychiatric morbidity of the adoptees was emphasized by HR (OR = 4.28, CI 2.14-8.56) and dysfunctional family processes (OR = 6.44, CI 2.75-15.04). In the LSES families, the adoptees´ psychiatric morbidity was almost significantly increased by HR (OR = 2.10, CI 0.99-4.45), but not by dysfunctional family processes (OR = 1.33, CI 0.53-3.34).

conclusionsThis study showed that in HSES families, dysfunctional family processes and HR for schizophrenia increased the likelihoods for the development of psychiatric disorders in adoptees. The results can be utilized in identifying risk factors in the development of psychiatric disorders and focusing preventative strategies on risk groups with acknowledging the importance of family functioning.

Indexed as

Mental DisordersSchizophreniaAdoptionFinlandGenetic Predisposition to DiseaseHumansRisk FactorsSocial ClassAdoption studyFamily functioningGene-environment interactionPsychiatric disordersSchizophreniaSocioeconomic status

Identifiers

PMID33398497
OpenAlexW3118671614

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.