Evidence map›Paper›PMID 33398458›Full record

ReviewWiener klinische Wochenschrift2021

Development of sustainable research excellence with a global perspective on infectious diseases: Centre de Recherches Médicales de Lambaréné (CERMEL), Gabon.

Michael Ramharter, Selidji T Agnandji, Ayôla A Adegnika, Bertrand Lell, Ghyslain Mombo-Ngoma, Martin P Grobusch, Matthew McCall, Riko Muranaka, Andrea Kreidenweiss, Thirumalaisamy P Velavan and 7 more

Abstract readReview
In one paragraph

Review in Wiener klinische Wochenschrift, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

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  10. The Performance of a Rapid Coronavirus Disease 2019 Antigen Test in Rural Gabon.The American journal of tropical medicine and hygiene · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Michael RamharterDepartment of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Dep. of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany. ramharter@bnitm.de.ORCID http://orcid.org/0000-0002-9259-1885
Selidji T AgnandjiCentre de Recherches Médicale de Lambaréné, Lambaréné, Gabon.
Ayôla A AdegnikaCentre de Recherches Médicale de Lambaréné, Lambaréné, Gabon.
Bertrand LellCentre de Recherches Médicale de Lambaréné, Lambaréné, Gabon.
Ghyslain Mombo-NgomaDepartment of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Dep. of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Martin P GrobuschCenter of Tropical Medicine and Travel Medicine, Amsterdam University Medical Centers, University of Amsterdam, Amsterdam, The Netherlands.
Matthew McCallCentre de Recherches Médicale de Lambaréné, Lambaréné, Gabon.
Riko MuranakaDepartment of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine & I. Dep. of Medicine University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Andrea KreidenweissInstitute of Tropical Medicine, Travel Medicine and Human Parasitology, University Clinics, Eberhard Karls University Tübingen, Tübingen, Germany.
Thirumalaisamy P VelavanInstitute of Tropical Medicine, Travel Medicine and Human Parasitology, University Clinics, Eberhard Karls University Tübingen, Tübingen, Germany.
Meral EsenInstitute of Tropical Medicine, Travel Medicine and Human Parasitology, University Clinics, Eberhard Karls University Tübingen, Tübingen, Germany.
Frieder SchaumburgInstitut für Medizinische Mikrobiologie, Universitätsklinikum Münster, Münster, Germany.
Abraham AlabiCentre de Recherches Médicale de Lambaréné, Lambaréné, Gabon.
Christiane DrumlMedical University of Vienna, Vienna, Austria.
Benjamin MordmüllerInstitute of Tropical Medicine, Travel Medicine and Human Parasitology, University Clinics, Eberhard Karls University Tübingen, Tübingen, Germany.
Carsten KöhlerInstitute of Tropical Medicine, Travel Medicine and Human Parasitology, University Clinics, Eberhard Karls University Tübingen, Tübingen, Germany.
Peter G KremsnerCentre de Recherches Médicale de Lambaréné, Lambaréné, Gabon.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Medical research in sub-Saharan Africa is of high priority for societies to respond adequately to local health needs. Often enough it remains a challenge to build up capacity in infrastructure and human resources to highest international standards and to sustain this over mid-term to long-term periods due to difficulties in obtaining long-term institutional core funding, attracting highly qualified scientists for medical research and coping with ever changing structural and political environments. The Centre de Recherches Médicales de Lambaréné (CERMEL) serves as model for how to overcome such challenges and to continuously increase its impact on medical care in Central Africa and beyond. Starting off as a research annex to the Albert Schweitzer Hospital in Lambaréné, Gabon, it has since then expanded its activities to academic and regulatory clinical trials for drugs, vaccines and diagnostics in the field of malaria, tuberculosis, and a wide range of poverty related and neglected tropical infectious diseases. Advancing bioethics in medical research in Africa and steadily improving its global networks and infrastructures, CERMEL serves as a reference centre for several international consortia. In close collaboration with national authorities, CERMEL has become one of the main training hubs for medical research in Central Africa. It is hoped that CERMEL and its leitmotiv "to improve medical care for local populations" will serve as an inspiration to other institutions in sub-Saharan Africa to further increase African capacity to advance medicine.

Indexed as

Biomedical ResearchCommunicable DiseasesTuberculosisGabonHumansPovertyCapacity developmentGabonMedical researchNeglected tropical diseasesSub-Saharan Africa

Identifiers

PMID33398458
PMCPMC7781170

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.