Evidence map›Paper›PMID 33398442›Full record

ReviewTopics in current chemistry (Cham)2021

Methods for Intracellular Delivery of Quantum Dots.

Sueden O Souza, Rafael B Lira, Cássia R A Cunha, Beate S Santos, Adriana Fontes, Goreti Pereira

Abstract readReview
PubMed Publisher
In one paragraph

Review in Topics in current chemistry (Cham), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Quantum dots for bone tissue engineering.Materials today. Bio · 2024
    Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sueden O SouzaDepartamento de Biofísica e Radiobiologia, Universidade Federal de Pernambuco, CB, UFPE, Av. Prof. Moraes Rego, S/N, Recife, PE, 50670-901, Brazil.
Rafael B LiraMoleculaire Biofysica, Zernike Instituut, Rijksuniversiteit Groningen, Groningen, The Netherlands.
Cássia R A CunhaLaboratório Federal de Defesa Agropecuária em Pernambuco, Recife, Brazil.
Beate S SantosDepartamento de Ciências Farmacêuticas, Universidade Federal de Pernambuco, Recife, Brazil.
Adriana FontesDepartamento de Biofísica e Radiobiologia, Universidade Federal de Pernambuco, CB, UFPE, Av. Prof. Moraes Rego, S/N, Recife, PE, 50670-901, Brazil. adriana.fontes@ufpe.br.
Goreti PereiraDepartamento de Química Fundamental, Universidade Federal de Pernambuco, CCEN, UFPE, Av. Jornalista Anibal Fernandes, S/N, Recife, 50740-560, PE, Brazil. goreti.pereira@ufpe.br.ORCID http://orcid.org/0000-0003-2604-6704

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Quantum dots (QDs) have attracted considerable attention as fluorescent probes for life sciences. The advantages of using QDs in fluorescence-based studies include high brilliance, a narrow emission band allowing multicolor labeling, a chemically active surface for conjugation, and especially, high photostability. Despite these advantageous features, the size of the QDs prevents their free transport across the plasma membrane, limiting their use for specific labeling of intracellular structures. Over the years, various methods have been evaluated to overcome this issue to explore the full potential of the QDs. Thus, in this review, we focused our attention on physical and biochemical QD delivery methods-electroporation, microinjection, cell-penetrating peptides, molecular coatings, and liposomes-discussing the benefits and drawbacks of each strategy, as well as presenting recent studies in the field. We hope that this review can be a useful reference source for researches that already work or intend to work in this area. Strategies for the intracellular delivery of quantum dots discussed in this review (electroporation, microinjection, cell-penetrating peptides, molecular coatings, and liposomes).

Indexed as

AnimalsCell-Penetrating PeptidesDrug CarriersDrug Delivery SystemsElectroporationFluorescent DyesHumansLiposomesMicroinjectionsQuantum DotsCell-Penetrating PeptidesDrug CarriersFluorescent DyesLiposomesCell-penetrating peptidesElectroporationIntracellular labelingLiposomesMicroinjectionSemiconductor nanocrystals

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.