Evidence map›Paper›PMID 33398364›Full record

ArticleMolecular medicine reports2021

9‑Hydroxy‑isoegomaketone inhibits LPS‑induced NO and inflammatory cytokine production in RAW264.7 cells.

Hyun Mi Kim, Bomi Nam, Sunil Babu Paudel, Joo-Won Nam, Ah-Reum Han, Hye Gwang Jeong, Chang Hyun Jin

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. Polyene Carboxylic Acids from aMolecules (Basel, Switzerland) · 2023
    Article
  3. Efficacy ofFrontiers in pharmacology · 2023
    Article
  4. Advances in the Pharmacological Activities and Effects of Perilla Ketone and Isoegomaketone.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Hyun Mi KimRadiation Breeding Research Team, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup‑si, Jeollabuk‑do 56212, Republic of Korea.
Bomi NamRadiation Breeding Research Team, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup‑si, Jeollabuk‑do 56212, Republic of Korea.
Sunil Babu PaudelCollege of Pharmacy, Yeungnam University, Gyengsan‑si, Gyeongsangbuk‑do 38541, Republic of Korea.
Joo-Won NamCollege of Pharmacy, Yeungnam University, Gyengsan‑si, Gyeongsangbuk‑do 38541, Republic of Korea.
Ah-Reum HanRadiation Breeding Research Team, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup‑si, Jeollabuk‑do 56212, Republic of Korea.
Hye Gwang JeongCollege of Pharmacy, Chungnam National University, Daejeon, Chungcheongnam‑do 34134, Republic of Korea.
Chang Hyun JinRadiation Breeding Research Team, Advanced Radiation Technology Institute, Korea Atomic Energy Research Institute, Jeongeup‑si, Jeollabuk‑do 56212, Republic of Korea.
Korea Atomic Energy Research Institute · KRYeungnam University · KRChungnam National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Isoegomaketone (IK) is a known component of

Indexed as

AnimalsFuransGene Expression Regulation, EnzymologicHeme Oxygenase-1InflammationInterferon-betaInterleukin-6KetonesLipopolysaccharidesMembrane ProteinsMiceNitric OxideRAW 264.7 CellsFuransHeme Oxygenase-1Hmox1 protein, mouseInterferon-betaInterleukin-6interleukin-6, mouseisoegomaketoneKetonesLipopolysaccharidesMembrane ProteinsNitric Oxide9‑hydroxy‑isoegomaketoneheme oxygenase‑1inflammationnuclear factor erythroid 2‑related factor 2Perilla frutescens

Identifiers

PMID33398364
PMCPMC7809899
OpenAlexW3114528238

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.