ArticleNature medicine2021
Pathophysiology-based subphenotyping of individuals at elevated risk for type 2 diabetes.
Open access · greenAbstract read
In one paragraph
Article in Nature medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 218 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
218citing papers in PubMed, 3 pooled it
40.1field-weighted citation impact, top 1% of its field
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
218 citing papers in PubMed, 3 syntheses or guidelines pooled it, 359 citations in OpenAlex.
- Surrogate measures of first-phase insulin secretion versus reference methods intravenous glucose tolerance test and hyperglycemic clamp: a systematic review and meta-analyses.BMJ open diabetes research & care · 2024Pooled it
- EASL-EASD-EASO Clinical Practice Guidelines on the Management of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).Obesity facts · 2024Guideline
- Risk prediction models for incident type 2 diabetes in Chinese people with intermediate hyperglycemia: a systematic literature review and external validation study.Cardiovascular diabetology · 2022Pooled it
- Prediabetes Subgroups, Type 2 Diabetes Risk, and Differential Effects of Preventive Interventions.The Journal of clinical endocrinology and metabolism · 2025 · on this mapTrial
- Gut microbiome predicts personalized responses to dietary fiber in prediabetes: a randomized, open-label trial.Nature communications · 2025Trial
- Body Composition Differentiates Prediabetes Phenotype Clusters in the Diabetes Prevention Program Study.The Journal of clinical endocrinology and metabolism · 2025Trial
- Baseline Characteristics of Weight-Loss Success in a Personalized Nutrition Intervention: A Secondary Analysis.Nutrients · 2025Trial
- Calanus Oil and Lifestyle Interventions Improve Glucose Homeostasis in Obese Subjects with Insulin Resistance.Marine drugs · 2025Trial
- Effect of broccoli sprout extract and baseline gut microbiota on fasting blood glucose in prediabetes: a randomized, placebo-controlled trial.Nature microbiology · 2025Trial
- Determinants of increased muscle insulin sensitivity of exercise-trained versus sedentary normal weight and overweight individuals.Science advances · 2025Trial
- Impact of obesity and type 2 diabetes on muscle power, quality, and force-velocity, and their relation to functional capacity.Journal of diabetes and metabolic disorders · 2026Article
- Data-Driven Clustering of Secretory Bone and Inflammatory Markers to Subphenotype Patients Undergoing Hemodialysis.Kidney international reports · 2026Article
- Metabolomics-Defined Subtypes of Prediabetes and Risk of Cardiovascular-Kidney-Metabolic Outcomes.Diabetes · 2026Article
- Prediabetes Subtypes with Divergent Iron Metabolism Profiles: A Cluster Analysis from Two Cohorts in the United States and China.Biological trace element research · 2026Article
- Unhealthy fat distribution as a sex-specific predictor of declining hippocampus insulin sensitivity.Diabetologia · 2026Article
- Type 2 diabetes subtypes for precision medicine: methodological challenges and alternative prediction-based approaches.Diabetologia · 2026Review
- Prediabetes Subtypes with Divergent Iron Metabolism Profiles: A Cluster Analysis from Two Cohorts in the United States and China.Biological trace element research · 2026Article
- Insulin resistance in the 21st century: new takes on an old problem-2025 Diabetes, Diabetes Care, and Diabetologia Expert Forum.Diabetologia · 2026Review
- Cardiovascular-Kidney-Metabolic Syndrome and Its Hepatic Dimension: A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Subtypes of pre-diabetes in rural adolescent girls from India (DERVAN-11).BMJ open diabetes research & care · 2026Article
158 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 4 countries.
Robert WagnerInstitute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany. robert.wagner@uni-tuebingen.de.ORCID http://orcid.org/0000-0002-6120-0191
Martin HeniInstitute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0002-8462-3832
Adam G TabákDepartment of Epidemiology and Public Health, University College London, London, UK.ORCID http://orcid.org/0000-0002-6234-3936
Jürgen MachannInstitute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0002-4458-5886
Fritz SchickGerman Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.
Elko RandrianarisoaInstitute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.
Martin Hrabě de AngelisGerman Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.ORCID http://orcid.org/0000-0002-7898-2353
Andreas L BirkenfeldInstitute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.
Norbert StefanInstitute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.ORCID http://orcid.org/0000-0002-2186-9595
Andreas PeterInstitute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.
Hans-Ulrich HäringInstitute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.
Andreas FritscheInstitute for Diabetes Research and Metabolic Diseases of the Helmholtz Center Munich at the University of Tübingen, Tübingen, Germany.
Deutsches Diabetes-Zentrum e.V. · DEHarvard University · USHelmholtz Zentrum München · DESemmelweis University · HU
Funding
Socio-economic status and heterogeneity in agingR01AG013196 · NIA · UNIVERSITY OF LONDON INST OF NEUROLOGY · PI MARMOT, MICHAEL G, SINGH-MANOUX, ARCHANA · 1996 to 2013
$3.5MSocioeconomic gradient in CHD in early old ageR01HL036310 · NHLBI · UNIVERSITY OF LONDON · PI KIVIMAKI, MIKA J, MARMOT, MICHAEL G · 1986 to 2012
$3.1MBritish Heart Foundation RG/13/2/30098Medical Research Council G0902037Medical Research Council MR/K013351/1Medical Research Council MR/R024227/1NHLBI NIH HHS R01 HL036310NIA NIH HHS R01 AG013196
Abstract
The state of intermediate hyperglycemia is indicative of elevated risk of developing type 2 diabetes
Indexed as
PhenotypeAnthropometryBlood GlucoseBody CompositionCohort StudiesDiabetes Mellitus, Type 2Disease ProgressionDisease SusceptibilityFemaleGlucose Tolerance TestHumansInsulinMaleMiddle AgedBlood GlucoseInsulin
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.