ArticleNature plants2021
Bacterial seed endophyte shapes disease resistance in rice.
Article in Nature plants, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 205 papers, 1 of them a synthesis that pooled it.
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Who cites it
205 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A Meta-Analysis Approach to Defining the Culturable Core of Plant Endophytic Bacterial Communities.Applied and environmental microbiology · 2022Pooled it
- Unlocking the power ofmSystems · 2026Article
- Molecular Bases and Genetic Design of Rice Disease Resistance for Optimized Yield and Sustainable Agriculture.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Review
- Endophytes Across the Plant Life Cycle: Potential Roles in Plant Protection, Litter Decomposition, and Nutrient Cycling.Plants (Basel, Switzerland) · 2026Review
- Tissue-Specific Bioactive Metabolites and Antioxidant Activity in Minicitrus (Antioxidants (Basel, Switzerland) · 2026Article
- Review
- Seed-borne bacteria-mediated seedling microbiome assembly: genetic and metabolic mechanisms of salt tolerance.Archives of microbiology · 2026Review
- Genomic Insights into ANI-dDDH Relationships inBiology · 2026Article
- Isolation and evaluation of candidate plant-protecting bacteria from rice seedlings asymptomatic to Burkholderia glumae infection.Scientific reports · 2026Article
- Seasonal variations and assembly patterns of endophytic communities of Rheum palmatum.BMC microbiology · 2026Article
- Morphological plasticity of endophytic Chitinophaga pinensis.Antonie van Leeuwenhoek · 2026Article
- Ability of Different Bacteria from Grapevine to ColonizePlants (Basel, Switzerland) · 2026Article
- What do we know about the seed microbiome?Microbiome · 2026Review
- Pre-Harvest Agronomic Reduction inToxins · 2026Article
- Seed-microbiome interactions: Mechanistic insights and utilization toward seed performance for sustainable agriculture.Plant communications · 2026Review
- The plant microbiota: From theoretical advances to applications.Fundamental research · 2026Review
- Translational microbiomes in agriculture: microbial communities as tools to effect host and system health for improved crop production.Applied and environmental microbiology · 2026Review
- Phenolic acid biosynthesis is associated with deleterious microbiome changes during Plasmodiophora brassicae-induced clubroot in pakchoi.Microbiome · 2026Article
- The Effects of Acorn Origin, Environmental Microbiomes and Local Adaptation on the Leaf Metabolome.Journal of chemical ecology · 2026Article
- Evaluating microbial community profiles of Chile peppers grown on the International Space Station provides implications for fruiting crops.Scientific reports · 2026Article
145 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cereal crop production is severely affected by seed-borne bacterial diseases across the world. Locally occurring disease resistance in various crops remains elusive. Here, we have observed that rice plants of the same cultivar can be differentiated into disease-resistant and susceptible phenotypes under the same pathogen pressure. Following the identification of a seed-endophytic bacterium as the resistance-conferring agent, integration of high-throughput data, gene mutagenesis and molecular interaction assays facilitated the discovery of the underlying mode of action. Sphingomonas melonis that is accumulated and transmitted across generations in disease-resistant rice seeds confers resistance to disease-susceptible phenotypes by producing anthranilic acid. Without affecting cell growth, anthranilic acid interferes with the sigma factor RpoS of the seed-borne pathogen Burkholderia plantarii, probably leading to impairment of upstream cascades that are required for virulence factor biosynthesis. The overall findings highlight the hidden role of seed endophytes in the phytopathology paradigm of 'disease triangles', which encompass the plant, pathogens and environmental conditions. These insights are potentially exploitable for modern crop cultivation threatened by globally widespread bacterial diseases.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.