ArticleNature human behaviour2021
Revisiting the global workspace orchestrating the hierarchical organization of the human brain.
Article in Nature human behaviour, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 1 of them a synthesis that pooled it.
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Who cites it
76 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A comprehensive analysis of brain network complexity in task-based fMRI using entropy: systematic review.Brain imaging and behavior · 2026Pooled it
- Neural integrator and orchestrator communities shape spontaneous signaling in the human brain.PNAS nexus · 2026Article
- A three-component dynamical index of consciousness-related neural organisation.Biological cybernetics · 2026Article
- Characteristic spatiotemporal features of large-scale functional network architecture in posttraumatic stress disorder.Translational psychiatry · 2026Article
- Modeled Long-Term Effects of Psilocybin on Dynamic Activity and Effective Connectivity of Fronto-Striatal-Thalamic Circuits.Human brain mapping · 2026Article
- Schooling Trajectories and the Development of Brain Dynamics: A Comparative Study of Montessori and Traditional Education.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- A canary in the mind: A single baseline brain scan predicts adolescent depression and anxiety one year later.medRxiv : the preprint server for health sciences · 2026Article
- Competitive interactions shape mammalian brain network dynamics and computation.Nature neuroscience · 2026Article
- Exploring the Role of the Rich Club in Network Control of Neurocognitive States.Human brain mapping · 2026Article
- Neural integrator and orchestrator communities shape spontaneous signaling in the human brain.bioRxiv : the preprint server for biology · 2026Article
- A Virtual Clinical Trial of Psychedelics to Treat Patients With Disorders of Consciousness.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- How the brain predicts timing: distinct network hubs for predicting and evaluating auditory sensory events.Frontiers in neuroscience · 2026Article
- Emergent multiscale organisation of neural dynamics fragments in anaesthesia.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- Qualia as control-theoretic constructs for autonomous agents: event phase space as an action-oriented semantic safety layer.Frontiers in robotics and AI · 2026Article
- Disrupted Brain Hierarchical Organization in Alzheimer's Disease Progression.medRxiv : the preprint server for health sciences · 2025Article
- Threat-related corticocortical connectivity elicited by rapid auditory looms.Scientific reports · 2025Article
- Deep learning and whole-brain networks for biomarker discovery: modeling the dynamics of brain fluctuations in resting-state and cognitive tasks.Scientific reports · 2025Article
- Reconfiguration of functional brain hierarchy in schizophrenia.Translational psychiatry · 2025Article
- Disrupted hierarchical organization in disorders of consciousness revealed by fluctuation-dissipation deviations.bioRxiv : the preprint server for biology · 2025Article
- Remodeling and Characterization Analysis of Corticospinal Tract in Patients with Intracerebral Hemorrhage in the Basal Ganglia.Translational stroke research · 2025Article
16 more citing papers are in PubMed but not listed here.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A central challenge in neuroscience is how the brain organizes the information necessary to orchestrate behaviour. Arguably, this whole-brain orchestration is carried out by a core subset of integrative brain regions, a 'global workspace', but its constitutive regions remain unclear. We quantified the global workspace as the common regions across seven tasks as well as rest, in a common 'functional rich club'. To identify this functional rich club, we determined the information flow between brain regions by means of a normalized directed transfer entropy framework applied to multimodal neuroimaging data from 1,003 healthy participants and validated in participants with retest data. This revealed a set of regions orchestrating information from perceptual, long-term memory, evaluative and attentional systems. We confirmed the causal significance and robustness of our results by systematically lesioning a generative whole-brain model. Overall, this framework describes a complex choreography of the functional hierarchical organization of the human brain.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.