Evidence map›Paper›PMID 33398038›Full record

ArticleCommunications biology2021

Excess extracellular K

Hong-Bo Zhao, Yan Zhu, Li-Man Liu

Abstract read
In one paragraph

Article in Communications biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. ATP-gated P2x7 receptors express at type II auditory nerves and required for efferent hearing control and noise protection.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hong-Bo ZhaoDept. of Otolaryngology, University of Kentucky Medical School, 800 Rose Street, Lexington, KY, 40536, USA. hzhao2@uky.edu.ORCID 0000-0002-1189-2142
Yan ZhuDept. of Otolaryngology, University of Kentucky Medical School, 800 Rose Street, Lexington, KY, 40536, USA.
Li-Man LiuDept. of Otolaryngology, University of Kentucky Medical School, 800 Rose Street, Lexington, KY, 40536, USA.

Funding

ATP-purinergic mechanisms underlying noise-induced cochlear synaptopathy and hearing lossR01DC017025 · NIDCD · YALE UNIVERSITY · PI ZHAO, HONG-BO · 2018 to 2022
$1.9M
Diagnosis of Noise-Induced Hidden Hearing LossR56DC016585 · NIDCD · UNIVERSITY OF KENTUCKY · PI EARL, BRIAN RICHARD, SHINN, JENNIFER B · 2018 to 2018
$317k
NIDCD NIH HHS R01 DC017025NIDCD NIH HHS R56 DC016585
6 · The paper itself

Abstract

Inner hair cell (IHC) ribbon synapses are the first synapse in the auditory system and can be degenerated by noise and aging, thereby leading to hidden hearing loss (HHL) and other hearing disorders. However, the mechanism underlying this cochlear synaptopathy remains unclear. Here, we report that elevation of extracellular K

Indexed as

AnimalsCalcium Channel BlockersExcitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsFemaleHair Cells, Auditory, InnerHearing Loss, Noise-InducedMaleMiceMice, Inbred CBAMolecular Targeted TherapyNoisePotassiumPotassium Channel BlockersRandom AllocationSynapsesCalcium Channel BlockersExcitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsPotassiumPotassium Channel Blockers

Identifiers

PMID33398038
PMCPMC7782724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.