Evidence map›Paper›PMID 33397712›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

Differential Contribution of Cadm1-Cadm3 Cell Adhesion Molecules to Peripheral Myelinated Axons.

Natasha Sukhanov, Anya Vainshtein, Yael Eshed-Eisenbach, Elior Peles

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 29 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Natasha SukhanovDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Anya VainshteinDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Yael Eshed-EisenbachDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel.
Elior PelesDepartment of Molecular Cell Biology, Weizmann Institute of Science, Rehovot, Israel peles@weizmann.ac.il.ORCID 0000-0002-3325-0597
Weizmann Institute of Science · IL

Funding

Somatodendritic Inhibition of Oligodendrocyte MyelinationR01NS097428 · NINDS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI CHAN, JONAH R, PELES, ELIOR · 2016 to 2020
$1.5M
NINDS NIH HHS R01 NS097428
6 · The paper itself

Abstract

Cell adhesion proteins of the Cadm (SynCAM/Necl) family regulate myelination and the organization of myelinated axons. In the peripheral nervous system (PNS), intercellular contact between Schwann cells and their underlying axons is believed to be mediated by binding of glial Cadm4 to axonal Cadm3 or Cadm2. Nevertheless, given that distinct neurons express different combinations of the Cadm proteins, the identity of the functional axonal ligand for Cadm4 remains to be determined. Here, we took a genetic approach to compare the phenotype of

Indexed as

AnimalsAxonsCell Adhesion Molecule-1Cell Adhesion MoleculesCell CommunicationImmunoglobulinsMiceMice, KnockoutNerve Fibers, MyelinatedNeurogliaPeripheral NervesCadm1 protein, mouseCADM3 protein, humanCell Adhesion Molecule-1Cell Adhesion MoleculesImmunoglobulinsaxon-glia interactioncell adhesionmyelinnode of RanvierSchwann cellsSynCAM

Identifiers

PMID33397712
PMCPMC7896006
OpenAlexW3118536823

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.