Evidence map›Paper›PMID 33397677›Full record

ArticleScience translational medicine2021

Stereotypic neutralizing V

Sang Il Kim, Jinsung Noh, Sujeong Kim, Younggeun Choi, Duck Kyun Yoo, Yonghee Lee, Hyunho Lee, Jongtak Jung, Chang Kyung Kang, Kyoung-Ho Song and 9 more

Open access · hybridAbstract read
In one paragraph

Article in Science translational medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
5.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 94 citations in OpenAlex.

  1. Article
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  4. Explore antibody repertoire in the era of AI.Acta biochimica et biophysica Sinica · 2025
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  20. The smallest functional antibody fragment: Ultralong CDR H3 antibody knob regions potently neutralize SARS-CoV-2.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 1 institution in 1 country.

Sang Il KimDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0002-0472-8010
Jinsung NohDepartment of Electrical and Computer Engineering, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0002-7167-8113
Sujeong KimDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0002-0575-3875
Younggeun ChoiDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0003-3494-9145
Duck Kyun YooDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0002-3341-4897
Yonghee LeeDepartment of Electrical and Computer Engineering, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0001-8095-408X
Hyunho LeeDepartment of Electrical and Computer Engineering, Seoul National University, Seoul 08826, Republic of Korea.ORCID 0000-0002-3251-2639
Jongtak JungDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Chang Kyung KangDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Kyoung-Ho SongDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0002-4517-3840
Pyoeng Gyun ChoeDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0003-0022-9625
Hong Bin KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0001-6262-372X
Eu Suk KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0001-7132-0157
Nam-Joong KimDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0001-6793-9467
Moon-Woo SeongDepartment of Laboratory Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.
Wan Beom ParkDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0003-0022-9625
Myoung-Don OhDepartment of Internal Medicine, Seoul National University College of Medicine, Seoul 03080, Republic of Korea.ORCID 0000-0002-2344-7695
Sunghoon KwonDepartment of Electrical and Computer Engineering, Seoul National University, Seoul 08826, Republic of Korea. skwon@snu.ac.kr jjhchung@snu.ac.kr.ORCID 0000-0003-3514-1738
Junho ChungDepartment of Biochemistry and Molecular Biology, Seoul National University College of Medicine, Seoul 03080, Republic of Korea. skwon@snu.ac.kr jjhchung@snu.ac.kr.ORCID 0000-0003-4873-8031
Seoul National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stereotypic antibody clonotypes exist in healthy individuals and may provide protective immunity against viral infections by neutralization. We observed that 13 of 17 patients with COVID-19 had stereotypic variable heavy chain (V

Indexed as

Antibodies, NeutralizingAntibodies, ViralClone CellsCOVID-19Enzyme-Linked Immunosorbent AssayHumansImmunoglobulin GImmunoglobulin Heavy ChainsImmunoglobulin Variable RegionMutationProtein BindingProtein DomainsRecombinant ProteinsSARS-CoV-2Spike Glycoprotein, CoronavirusAntibodies, NeutralizingAntibodies, ViralImmunoglobulin GImmunoglobulin Heavy ChainsImmunoglobulin Variable RegionRecombinant ProteinsSpike Glycoprotein, Coronavirusspike protein, SARS-CoV-2

Identifiers

PMID33397677
PMCPMC7875332
OpenAlexW3119027829

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.