Evidence map›Paper›PMID 33397653›Full record

ReviewThe British journal of ophthalmology2022

Choroidal macrovessels: multimodal imaging findings and review of the literature.

Beatrice Gallo, Samantha R de Silva, Omar A Mahroo, Zubin Saihan, Praveen J Patel, Jonathan G Dowler, Carlos Pavesio, Pearse A Keane, Adnan Tufail, Mandeep S Sagoo

Open access · hybridAbstract readReview
In one paragraph

Review in The British journal of ophthalmology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Frontiers in physiology · 2023
    Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 2 countries.

Beatrice GalloOcular Oncology Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK beatricegallo.bg@gmail.com.ORCID 0000-0001-6862-6227
Samantha R de SilvaMedical Retina Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Omar A MahrooMedical Retina Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.ORCID 0000-0003-1254-0832
Zubin SaihanMedical Retina Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Praveen J PatelMedical Retina Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.ORCID 0000-0001-8682-4067
Jonathan G DowlerMedical Retina Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Carlos PavesioMedical Retina Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Pearse A KeaneMedical Retina Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Adnan TufailMedical Retina Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Mandeep S SagooOcular Oncology Service, Moorfields Eye Hospital NHS Foundation Trust, London, UK.
Moorfields Eye Hospital NHS Foundation Trust · GB

Funding

Department of Health CS-2014-14-023Medical Research Council MC_PC_19005Medical Research Council MR/T019050/1Wellcome Trust 206619/Z/17/Z
6 · The paper itself

Abstract

BACKGROUND/

aimsTo describe clinical and multimodal imaging features in a cohort of choroidal macrovessels.

methodsDemographics and multimodal imaging features of 16 eyes of 13 patients with choroidal macrovessels were reviewed. The multimodal imaging included colour fundus photography, fundus autofluorescence (FAF), spectral domain enhanced depth imaging optical coherence tomography (OCT), en face OCT, OCT-angiography (OCT-A), B-scan ultrasonography (US), fluorescein angiography (FFA) and indocyanine green angiography (ICGA).

resultsThree patients had bilateral involvement. On colour fundus photography, three patterns were evident (a clearly visible orange-red vessel; a track of pigmentary changes; spots of mild pigmentary changes). Vessel orientation was horizontal (11 eyes), oblique (4 eyes) or vertical (1 eye). In 2 eyes, the vessel was extra-macular. OCT in all cases showed a hyporeflective choroidal area with posterior shadowing and elevation of the overlying retina. Subretinal fluid was present in 4 eyes. FAF (12 eyes) was normal (7 eyes) or showed a hypofluorescent/hyperfluorescent track (4 eyes) or linear hyperautofluorescence (1 eye). En-face OCT (2 eyes) revealed the course of the macrovessel at the level of choroid and choriocapillaris. On OCT-A (2 eyes) the vessel had a reflectivity similar to surrounding vessels but larger diameter. B-scan US (8 eyes) showed a nodular hypoechogenic lesion. FFA (5 eyes) showed early focal hyperfluorescence (4 eyes) not increasing in later phases, or was normal (1 eye). ICGA (6 eyes) showed early hyperfluorescence of the vessel.

conclusionsChoroidal macrovessels can mimic other entities, leading to underdiagnosis. Appreciating relevant features on different imaging modalities will aid a correct diagnosis.

Indexed as

ChoroidTomography, Optical CoherenceDiagnostic Techniques, OphthalmologicalFluorescein AngiographyHumansMultimodal ImagingRetrospective Studieschoroiddiagnostic tests/investigationretina

Identifiers

PMID33397653
PMCPMC8961769
OpenAlexW3120314334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.