Evidence map›Paper›PMID 33397347›Full record

ArticleBMC musculoskeletal disorders2021

Surgical outcomes of the thoracic ossification of ligamentum flavum: a retrospective analysis of 61 cases.

Tsuyoshi Yamada, Shigeo Shindo, Toshitaka Yoshii, Shuta Ushio, Kazuo Kusano, Norihiko Miyake, Yoshiyasu Arai, Kazuyuki Otani, Atsushi Okawa, Osamu Nakai

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 32 citations in OpenAlex.

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  6. [Short-term effectiveness of floating island laminectomy surgery for thoracic spinal stenosis and myelopathy caused by ossification of ligamentum flavum].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Tsuyoshi YamadaDepartment of Orthopaedic Surgery, Kudanzaka Hospital, 1-6-12 Kudan- minami, Chiyoda-ku, 102-0074, Tokyo, Japan. yamada.orth@tmd.ac.jp.
Shigeo ShindoDepartment of Orthopaedic Surgery, Kudanzaka Hospital, 1-6-12 Kudan- minami, Chiyoda-ku, 102-0074, Tokyo, Japan.
Toshitaka YoshiiDepartment of Orthopaedic Surgery, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8510, Japan.
Shuta UshioDepartment of Orthopaedic Surgery, Kudanzaka Hospital, 1-6-12 Kudan- minami, Chiyoda-ku, 102-0074, Tokyo, Japan.
Kazuo KusanoDepartment of Orthopaedic Surgery, Kudanzaka Hospital, 1-6-12 Kudan- minami, Chiyoda-ku, 102-0074, Tokyo, Japan.
Norihiko MiyakeDepartment of Orthopaedic Surgery, Kudanzaka Hospital, 1-6-12 Kudan- minami, Chiyoda-ku, 102-0074, Tokyo, Japan.
Yoshiyasu AraiDepartment of Orthopaedic Surgery, Saiseikai Kawaguchi General Hospital, 5-11-5 Nishikawaguchi, 332-8558, Kawaguchi-city, Saitama, Japan.
Kazuyuki OtaniDepartment of Orthopaedic Surgery, Kudanzaka Hospital, 1-6-12 Kudan- minami, Chiyoda-ku, 102-0074, Tokyo, Japan.
Atsushi OkawaDepartment of Orthopaedic Surgery, Graduate School, Tokyo Medical and Dental University, Tokyo, 113-8510, Japan.
Osamu NakaiDepartment of Orthopaedic Surgery, Kudanzaka Hospital, 1-6-12 Kudan- minami, Chiyoda-ku, 102-0074, Tokyo, Japan.
Kudanzaka Hospital · JPTokyo Medical and Dental University · JPNoguchi Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThoracic ossification of ligamentum flavum (T-OLF), as one of the causes of thoracic myelopathy, is often combined with other spinal disorders. Concurrent lumbar spinal canal stenosis (LCS) is often obscured by symptoms due to T-OLF, leading to difficulty in identifying the origin of these neurological findings. It is common to be misdiagnosed or delayed diagnosis due to the complicated nature. We evaluated the prevalence, distribution, and clinical characteristics of OLF, especially in patients with LCS.

methodsThe authors performed a retrospective analysis of the outcomes of 61 patients who underwent thoracic surgeries performed for symptomatic T-OLF. In all the patients, whole spine lesions were evaluated preoperatively. We examined the factors related to poor outcomes (the recovery rate of the Japanese Orthopedic Association score for thoracic myelopathy is less than 40%) following OLF surgeries. We compared the clinical outcomes according to whether there was concurrent LCS, and determined the optimal surgical approach.

resultsThe occurrence of T-OLF increased with age. Forty-six cases (75.4%) were considered to be tandem T-OLF and LCS (LCS group). An advanced age, and concurrent LCS were associated with a poor outcome after the surgery. The LCS group significantly included a greater number of elderly, and more light-weighted patients with Modic change in thoracic spine and a greater sagittal vertical axis, resulting in the lower neurological recovery. Additional lumbar surgery (13cases) effectively improved both the T-JOA and L-JOA scores (from 6.5 ± 2.0 points to 8.0 ± 1.8 points, p = 0.0406, and from 14.5 ± 4.7 points to 20.7 ± 2.6 points, p = 0.001, respectively) in OLF patients with LCS.

conclusionsT-OLF was highly associated with other spinal disorders. Poor outcomes in T-OLF surgery could be associated with age and concurrent LCS, and an additional surgery for another lumbar lesion significantly improved neurological findings in T-OLF patients.

Indexed as

Ligamentum FlavumOssification, HeterotopicAgedDecompression, SurgicalHumansOsteogenesisRetrospective StudiesThoracic VertebraeTreatment OutcomeLumbar spinal canal stenosisOssification of the ligamentum flavumSpine surgeryTandem spinal stenosisThoracic myelopathy

Identifiers

PMID33397347
PMCPMC7784257
OpenAlexW3119391158

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.