Evidence map›Paper›PMID 33397203›Full record

ArticleJournal of neurotrauma2021

Association of Previous Concussion with Hippocampal Volume and Symptoms in Collegiate-Aged Athletes.

Timothy B Meier, Lezlie Y España, Alexander J Kirk, Amy M Nader, Jennifer E Powell, Lindsay D Nelson, Andrew R Mayer, Benjamin L Brett

Abstract read
In one paragraph

Article in Journal of neurotrauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
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  5. Review
  6. Article
  7. Article
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  9. Article
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  11. Article
  12. Article
  13. Article
  14. Comparison of Various Metrics of Repetitive Head Impact Exposure And Their Associations With Neurocognition in Collegiate-Aged Athletes.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Neurotrauma: 2022 update.Free neuropathology · 2022
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Timothy B MeierDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Lezlie Y EspañaDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Alexander J KirkDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Amy M NaderDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Jennifer E PowellDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Lindsay D NelsonDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.
Andrew R MayerThe Mind Research Network/Lovelace Biomedical and Environmental Research Institute, Neurology and Psychiatry Departments, University of New Mexico School of Medicine, Department of Psychology, University of New Mexico, Albuquerque, New Mexico, USA.
Benjamin L BrettDepartment of Neurosurgery, Medical College of Wisconsin, Milwaukee, Wisconsin, USA.

Funding

The role of neuroactive kynurenine metabolites in the chronic sequelae of concussion and contact sport exposureR01NS102225 · NINDS · MEDICAL COLLEGE OF WISCONSIN · PI MEIER, TIMOTHY B. · 2018 to 2022
$1.8M
NINDS NIH HHS R01 NS102225
6 · The paper itself

Abstract

There is concern that previous concussion and contact-sport exposure may have negative effects on brain structure and function. Accurately quantifying previous concussion is complicated by the fact that multiple definitions exist, with recent definitions allowing for diagnosis based on the presence of symptoms alone (Concussion in Sport Group criteria; CISG) rather than the presence of acute injury characteristics such as alterations in mental status (American Congress of Rehabilitation Medicine criteria; ACRM). The goals of the current work were to determine the effects of previous concussion and contact-sport exposure on gray matter structure and clinical measures in healthy, young-adult athletes and determine the extent to which these associations are influenced by diagnostic criteria used to retrospectively quantify concussions. One-hundred eight collegiate-aged athletes were enrolled; 106 athletes were included in final analyses (age, 21.37 ± 1.69; 33 female). Participants completed a clinical battery of self-report and neurocognitive measures and magnetic resonance imaging to quantify subcortical volumes and cortical thickness. Semistructured interviews were conducted to measure exposure to contact sports and the number of previous concussions based on CISG and ACRM criteria. There was a significant association of concussion-related and psychological symptoms with previous concussions based on ACRM (

Indexed as

AthletesAthletic InjuriesBrain ConcussionFemaleHippocampusHumansMaleMental Status and Dementia TestsYoung Adultconcussionhippocampusmild traumatic brain injuryrepetitive head impacts

Identifiers

PMID33397203
PMCPMC8082726

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.