Evidence map›Paper›PMID 33397044›Full record

ArticleEndocrinology and metabolism (Seoul, Korea)2020

Efficacy of Intraoperative Neuromonitoring in Reoperation for Recurrent Thyroid Cancer Patients.

Jang-Il Kim, Su-Jin Kim, Zhen Xu, JungHak Kwak, Jong-Hyuk Ahn, Hyeong Won Yu, Young Jun Chai, June Young Choi, Kyu Eun Lee

Registry-linked trialOpen access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Endocrinology and metabolism (Seoul, Korea), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06002984 (Effectiveness of Intraoperative Neuromonitoring to Identify and Preserve External Branch of Superior Laryngeal Nerve During Thyroid Surgery), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06002984 narecruitingnot on this mapstarted 2023, after this paper: background citation

Effectiveness of Intraoperative Neuromonitoring to Identify and Preserve External Branch of Superior Laryngeal Nerve During Thyroid Surgery

TypeinterventionalSponsorSeoul National University HospitalRan2023 to 2026Enrolled94ConditionsLaryngeal Nerve Injuries, Thyroidectomy, Voice ChangeArmsUsing Neuromonitoring to find EBSLN
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 3 countries.

Jang-Il KimDepartment of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Su-Jin KimDepartment of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Zhen XuDepartment of Surgery, Seoul National University College of Medicine, Seoul, Korea.
JungHak KwakDepartment of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Jong-Hyuk AhnDepartment of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Hyeong Won YuDepartment of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.
Young Jun ChaiDepartment of Surgery, Seoul Metropolitan Government Seoul National University Boramae Medical Center, Seoul, Korea.
June Young ChoiDepartment of Surgery, Seoul National University Bundang Hospital, Seongnam, Korea.
Kyu Eun LeeDepartment of Surgery, Seoul National University College of Medicine, Seoul, Korea.
Seoul National University · KRSeoul National University Bundang Hospital · KR

Funding

Ministry of Science and ICT IITP-2020-2018-0-01833
6 · The paper itself

Abstract

backgroundThe use of intraoperative neuromonitoring (IONM) in thyroid surgery to preserve recurrent laryngeal nerve (RLN) function has been widely accepted. We aimed to evaluate the usefulness of IONM in reoperation for recurrent thyroid cancer patients to help identify the RLN and prevent vocal cord palsy (VCP).

methodsWe analyzed 121 consecutive patients (with IONM group, 48 patients; without IONM group, 73 patients) who underwent reoperation for recurrent thyroid cancer after total thyroidectomy from January 2009 to March 2019 in our institution without VCP due to previous operations. Data including age, sex, number of previous operations, histologic subtype of the malignancy at the initial operation, operation time, RLNs at risk, difficulty of RLN identification, surgical procedure, VCP, and other postoperative complications were reviewed. Vocal cord movement evaluations were performed preoperatively and at 2 weeks postoperatively to evaluate RLN function. In patients with VCP, additional evaluations were performed. VCP exceeding 12 months after surgery was considered permanent VCP.

resultsVCP was observed in six (12.5%) and 16 (21.9%) patients with and without IONM (P=0.189). Transient and permanent VCP were found in three (6.3%) and three (6.3%) patients with IONM (P=0.098 and P=0.982, respectively) versus in 12 (16.4%) and four (5.5%) patients without IONM.

conclusionThe incidence of transient VCP seems to be lower in reoperations with IONM; however, there was no statistical significances. Further study will be needed to ascertain the efficacy of IONM in reoperation for recurrent thyroid cancer patients.

Indexed as

AdultAgedAged, 80 and overFemaleHumansIncidenceMaleMiddle AgedMonitoring, IntraoperativeOperative TimePostoperative ComplicationsRecurrent Laryngeal Nerve InjuriesReoperationRepublic of KoreaRetrospective StudiesThyroidectomyRecurrenceRecurrent laryngeal nerveReoperationThyroid neoplasmsVocal cord paralysis

Identifiers

PMID33397044
PMCPMC7803609
OpenAlexW3115186981

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.