Evidence map›Paper›PMID 33396826›Full record

ReviewInternational journal of molecular sciences2020

The Signaling Pathways Involved in the Anticonvulsive Effects of the Adenosine A

Jeroen Spanoghe, Lars E Larsen, Erine Craey, Simona Manzella, Annelies Van Dycke, Paul Boon, Robrecht Raedt

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Comparative analysis of adenosine 1 receptor expression and function in hippocampal and hypothalamic neurons.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2025
    Article
  8. Selective modulation of epileptic tissue by an adenosine ABritish journal of pharmacology · 2024
    Article
  9. Review
  10. β-Lapachone Exerts Hypnotic Effects via Adenosine ABiomolecules & therapeutics · 2024
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Design, synthesis and evaluation of amino-3,5-dicyanopyridines and thieno[2,3-b]pyridines as ligands of adenosine AMedicinal chemistry research : an international journal for rapid communications on design and mechanisms of action of biologically active agents · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jeroen Spanoghe4Brain, Department of Head and Skin, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-4427-0948
Lars E Larsen4Brain, Department of Head and Skin, Ghent University, 9000 Ghent, Belgium.
Erine Craey4Brain, Department of Head and Skin, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-6052-6325
Simona Manzella4Brain, Department of Head and Skin, Ghent University, 9000 Ghent, Belgium.
Annelies Van DyckeDepartment of Neurology, General Hospital Sint-Jan Bruges, 8000 Bruges, Belgium.
Paul Boon4Brain, Department of Head and Skin, Ghent University, 9000 Ghent, Belgium.
Robrecht Raedt4Brain, Department of Head and Skin, Ghent University, 9000 Ghent, Belgium.ORCID 0000-0002-8939-0169
Ghent University · BEAZ Sint-Jan · BE

Funding

Fonds Wetenschappelijk Onderzoek G042219N
6 · The paper itself

Abstract

Adenosine acts as an endogenous anticonvulsant and seizure terminator in the brain. Many of its anticonvulsive effects are mediated through the activation of the adenosine A

Indexed as

Signal TransductionAdenosine A1 Receptor AgonistsAnimalsAnticonvulsantsHumansReceptor, Adenosine A1SeizuresAdenosine A1 Receptor AgonistsAnticonvulsantsReceptor, Adenosine A1adenosineadenosine A1 receptorepilepsyinhibitionneuromodulationsignaling pathways

Identifiers

PMID33396826
PMCPMC7794785
OpenAlexW3115374334

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.