Evidence map›Paper›PMID 33396824›Full record

ArticlePathogens (Basel, Switzerland)2020

An Ultra-Sensitive Technique: Using

Laila R A Barbosa, Emanuelle L da Silva, Anne C G de Almeida, Yanka E A R Salazar, André M Siqueira, Maria das Graças Costa Alecrim, José Luiz Fernandes Vieira, Quique Bassat, Marcus V G de Lacerda, Wuelton M Monteiro and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact, top 76% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Review
  3. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Laila R A BarbosaFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-200, AM, Brazil.ORCID 0000-0001-8480-0352
Emanuelle L da SilvaFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-200, AM, Brazil.
Anne C G de AlmeidaFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-200, AM, Brazil.
Yanka E A R SalazarFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-200, AM, Brazil.ORCID 0000-0002-5084-7707
André M SiqueiraFiocruz-Manguinhos-Fundação Oswaldo Cruz, Instituto de Pesquisa Clínica Evandro Chagas, Rio de Janeiro 21040-900, RJ, Brazil.ORCID 0000-0003-2208-0294
Maria das Graças Costa AlecrimFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-200, AM, Brazil.
José Luiz Fernandes VieiraInstituto de Ciências da Saúde, Universidade Federal do Pará, Belém 66010-010, PA, Brazil.
Quique BassatISGlobal, Hospital Clínic, Universitat de Barcelona, 08036 Barcelona, Spain.
Marcus V G de LacerdaFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-200, AM, Brazil.
Wuelton M MonteiroFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-200, AM, Brazil.
Gisely C MeloFundação de Medicina Tropical Dr. Heitor Vieira Dourado, Instituto de Pesquisa Clínica Carlos Borborema, Manaus 69040-200, AM, Brazil.
Fundação de Medicina Tropical · BRFundação Oswaldo Cruz · BRInstitució Catalana de Recerca i Estudis Avançats · ESUniversidade Federal do Pará · BR

Funding

Coordenação de 255 Aperfeiçoamento de Pessoal de Nível Superior - Brasil 001Research Support Foundation of Amazonas PAPAC 005/2019
6 · The paper itself

Abstract

backgroundEarly recurrence of

methodsAn ultra-sensitive qPCR that targeted mitochondrial DNA was used to compare a standard qPCR that targeted 18S rDNA to detect early recurrence of

resultsOut of a total of 312 cases, 29 samples (9.3%) were characterized as recurrences, from which 3.2% (10/312) were only detected through ultra-sensitive qPCR testing.

conclusionsStudies that report the detection of

Indexed as

chloroquine resistancemalaria diagnosismitochondrial DNAsubmicroscopic infection

Identifiers

PMID33396824
PMCPMC7823330
OpenAlexW3113911424

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.