Evidence map›Paper›PMID 33396815›Full record

ReviewInternational journal of molecular sciences2020

Radon Exposure-Therapeutic Effect and Cancer Risk.

Andreas Maier, Julia Wiedemann, Felicitas Rapp, Franziska Papenfuß, Franz Rödel, Stephanie Hehlgans, Udo S Gaipl, Gerhard Kraft, Claudia Fournier, Benjamin Frey

Open access · goldAbstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
8.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 81 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Experimental Setups for In Vitro Studies on Radon Exposure in Mammalian Cells-A Critical Overview.International journal of environmental research and public health · 2023
    Review
  16. Radon Solubility in Different Tissues after Short Term Exposure.International journal of environmental research and public health · 2023
    Article
  17. Article
  18. Article
  19. Radon Progeny Adsorption on Facial Masks.International journal of environmental research and public health · 2022
    Article
  20. Changes in Sulfur Metabolism in Mouse Brains following Radon Inhalation.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Andreas MaierBiophysics Department, GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291 Darmstadt, Germany.ORCID 0000-0003-1309-5435
Julia WiedemannBiophysics Department, GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291 Darmstadt, Germany.
Felicitas RappBiophysics Department, GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291 Darmstadt, Germany.ORCID 0000-0003-0968-1546
Franziska PapenfußBiophysics Department, GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291 Darmstadt, Germany.
Franz RödelDepartment of Radiotherapy and Oncology, University Hospital Frankfurt, Goethe-Universität Frankfurt am Main, 60590 Frankfurt am Main, Germany.
Stephanie HehlgansDepartment of Radiotherapy and Oncology, University Hospital Frankfurt, Goethe-Universität Frankfurt am Main, 60590 Frankfurt am Main, Germany.ORCID 0000-0002-6816-3450
Udo S GaiplTranslational Radiation Biology, Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.ORCID 0000-0001-6375-5476
Gerhard KraftBiophysics Department, GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291 Darmstadt, Germany.
Claudia FournierBiophysics Department, GSI Helmholtzzentrum für Schwerionenforschung GmbH, 64291 Darmstadt, Germany.
Benjamin FreyTranslational Radiation Biology, Department of Radiation Oncology, Universitätsklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91054 Erlangen, Germany.ORCID 0000-0001-6743-3351
GSI Helmholtz Centre for Heavy Ion Research · DEFriedrich-Alexander-Universität Erlangen-Nürnberg · DEGoethe University Frankfurt · DE

Funding

Bundesministerium für Bildung und Forschung 02NUK050EURADON - Verein Europäische Radonheilbäder e. V. Fournier, Frey
6 · The paper itself

Abstract

Largely unnoticed, all life on earth is constantly exposed to low levels of ionizing radiation. Radon, an imperceptible natural occurring radioactive noble gas, contributes as the largest single fraction to radiation exposure from natural sources. For that reason, radon represents a major issue for radiation protection. Nevertheless, radon is also applied for the therapy of inflammatory and degenerative diseases in galleries and spas to many thousand patients a year. In either case, chronic environmental exposure or therapy, the effect of radon on the organism exposed is still under investigation at all levels of interaction. This includes the physical stage of diffusion and energy deposition by radioactive decay of radon and its progeny and the biological stage of initiating and propagating a physiologic response or inducing cancer after chronic exposure. The purpose of this manuscript is to comprehensively review the current knowledge of radon and its progeny on physical background, associated cancer risk and potential therapeutic effects.

Indexed as

Air Pollution, IndoorAnimalsClinical Trials as TopicEnvironmental ExposureHumansNeoplasmsRadiation ExposureRadiation MonitoringRadonRisk AssessmentRisk FactorsRadonanti-inflammatory effectschanges immune activationclinical studieslow dosesosteoimmunological changesradon therapyα-particles

Identifiers

PMID33396815
PMCPMC7796069
OpenAlexW3115019252

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.