Evidence map›Paper›PMID 33396793›Full record

ArticleMolecules (Basel, Switzerland)2020

New Bioactive Peptides Identified from a Tilapia Byproduct Hydrolysate Exerting Effects on DPP-IV Activity and Intestinal Hormones Regulation after Canine Gastrointestinal Simulated Digestion.

Sandy Theysgeur, Benoit Cudennec, Barbara Deracinois, Claire Perrin, Isabelle Guiller, Anne Lepoudère, Christophe Flahaut, Rozenn Ravallec

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 48 citations in OpenAlex.

  1. Circular Valorization of Yellowfin Tuna (Molecules (Basel, Switzerland) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Bioactive peptides extracted from hydrolyzed animal byproducts for dogs and cats.Animal frontiers : the review magazine of animal agriculture · 2024
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Sandy TheysgeurUMR-T 1158, BioEcoAgro, University of Lille, F-59000 Lille, France.
Benoit CudennecUMR-T 1158, BioEcoAgro, University of Lille, F-59000 Lille, France.ORCID 0000-0002-5505-4458
Barbara DeracinoisUMR-T 1158, BioEcoAgro, University of Lille, F-59000 Lille, France.ORCID 0000-0002-0279-2449
Claire PerrinDiana Pet Food, F-56250 Elven, France.
Isabelle GuillerDiana Pet Food, F-56250 Elven, France.
Anne LepoudèreDiana Pet Food, F-56250 Elven, France.
Christophe FlahautUMR-T 1158, BioEcoAgro, University of Lille, F-59000 Lille, France.ORCID 0000-0002-2603-962X
Rozenn RavallecUMR-T 1158, BioEcoAgro, University of Lille, F-59000 Lille, France.
Université de Lille · FR

Funding

Agence Nationale de la Recherche ANR-11-EQPX-0037
6 · The paper itself

Abstract

Like their owners, dogs and cats are more and more affected by overweight and obesity-related problems and interest in functional pet foods is growing sharply. Through numerous studies, fish protein hydrolysates have proved their worth to prevent and manage obesity-related comorbidities like diabetes. In this work, a human in vitro static simulated gastrointestinal digestion model was adapted to the dog which allowed us to demonstrate the promising effects of a tilapia byproduct hydrolysate on the regulation of food intake and glucose metabolism. Promising effects on intestinal hormones secretion and dipeptidyl peptidase IV (DPP-IV) inhibitory activity were evidenced. We identify new bioactive peptides able to stimulate cholecystokinin (CCK) and glucagon-like peptide 1 (GLP-1) secretions, and to inhibit the DPP-IV activity after a transport study through a Caco-2 cell monolayer.

Indexed as

Animal FeedAnimalsBiological TransportCaco-2 CellsCat DiseasesCatsCholecystokininDipeptidyl Peptidase 4Dog DiseasesDogsFish ProductsGastrointestinal HormonesGastrointestinal TractGlucagon-Like Peptide 1GlucoseHumansCholecystokininDipeptidyl Peptidase 4DPP4 protein, humanGastrointestinal HormonesGlucagon-Like Peptide 1GlucosePeptidesProtein Hydrolysatesbioactive peptidescholecystokininDPP-IV inhibitory peptidesfish byproduct hydrolysateglucagon-like peptide 1in vitro gastrointestinal digestion

Identifiers

PMID33396793
PMCPMC7796187
OpenAlexW3115581497

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.