Imaging Sequences for Hyperpolarized Solids.

Xudong Lv, Jeffrey Walton, Emanuel Druga, Raffi Nazaryan, Haiyan Mao, Alexander Pines, Ashok Ajoy, Jeffrey Reimer

Abstract read

In one paragraph

Article in Molecules (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Ultrafast Magic Angle Spinning Solid-State NMR Spectroscopy: Advances in Methodology and Applications.Chemical reviews · 2023
Review

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xudong LvDepartment of Chemistry, University of California, Berkeley, CA 94720, USA.ORCID 0000-0002-5601-3789

Jeffrey WaltonNuclear Magnetic Resonance Facility, University of California Davis, Davis, CA 95616, USA.ORCID 0000-0002-2359-955X

Emanuel DrugaDepartment of Chemistry, University of California, Berkeley, CA 94720, USA.

Raffi NazaryanDepartment of Chemistry, University of California, Berkeley, CA 94720, USA.

Haiyan MaoDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA 94720, USA.

Alexander PinesDepartment of Chemistry, University of California, Berkeley, CA 94720, USA.

Ashok AjoyDepartment of Chemistry, University of California, Berkeley, CA 94720, USA.

Jeffrey ReimerDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, CA 94720, USA.ORCID 0000-0002-4191-3725

Funding

National Science Foundation 1903803NIH HHS 1S10RR013871-01A1

6 · The paper itself

Abstract

Hyperpolarization is one of the approaches to enhance Nuclear Magnetic Resonance (NMR) and Magnetic Resonance Imaging (MRI) signal by increasing the population difference between the nuclear spin states. Imaging hyperpolarized solids opens up extensive possibilities, yet is challenging to perform. The highly populated state is normally not replenishable to the initial polarization level by spin-lattice relaxation, which regular MRI sequences rely on. This makes it necessary to carefully "budget" the polarization to optimize the image quality. In this paper, we present a theoretical framework to address such challenge under the assumption of either variable flip angles or a constant flip angle. In addition, we analyze the gradient arrangement to perform fast imaging to overcome intrinsic short decoherence in solids. Hyperpolarized diamonds imaging is demonstrated as a prototypical platform to test the theory.

Indexed as

AlgorithmsCalibrationCarbon IsotopesDiamondEquipment DesignFourier AnalysisImage Processing, Computer-AssistedMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMagneticsPhantoms, ImagingSignal-To-Noise RatioCarbon-13Carbon IsotopesDiamondflip anglehyperpolarizationmagnetic resonance imaging

Identifiers

PMID33396762

DOI10.3390/molecules26010133

PMCPMC7795150

What OpenQuestion holds

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LicenceCC BY

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.