Evidence map›Paper›PMID 33396739›Full record

ReviewCancers2020

Exosomes: Their Role in Pathogenesis, Diagnosis and Treatment of Diseases.

Houssam Aheget, Loubna Mazini, Francisco Martin, Boutaïna Belqat, Juan Antonio Marchal, Karim Benabdellah

Abstract readReview
In one paragraph

Review in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Article
  9. Review
  10. Review
  11. Migrasomes: A Novel Target for Cancer Treatment.Current cancer drug targets · 2026
    Review
  12. Review
  13. Review
  14. Role of Seminal Exosomes in Reproduction.Journal of cellular physiology · 2025
    Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Review
  20. Review

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Houssam AhegetGENYO Centre for Genomics and Oncological Research, Genomic Medicine Department, Pfizer/University of Granada/Andalusian Regional Government, Health Sciences Technology Park, Av. de la Illustration 114, 18016 Granada, Spain.ORCID 0000-0003-3362-1519
Loubna MaziniCenter of Biological and Medical Sciences (CIAM), Mohammed VI Polytechnic University, Ben-Guerir 43152, Morocco.
Francisco MartinGENYO Centre for Genomics and Oncological Research, Genomic Medicine Department, Pfizer/University of Granada/Andalusian Regional Government, Health Sciences Technology Park, Av. de la Illustration 114, 18016 Granada, Spain.ORCID 0000-0003-1961-8612
Boutaïna BelqatDepartment of Biology, Faculty of Sciences, University Abdelmalek Essaâdi, Tétouan 93000, Morocco.
Juan Antonio MarchalBiomedical Research Institute (ibs. GRANADA), 18012 Granada, Spain.ORCID 0000-0002-4996-8261
Karim BenabdellahGENYO Centre for Genomics and Oncological Research, Genomic Medicine Department, Pfizer/University of Granada/Andalusian Regional Government, Health Sciences Technology Park, Av. de la Illustration 114, 18016 Granada, Spain.ORCID 0000-0003-4673-2111

Funding

Instituto de Salud Carlos III PI12/01097, PI15/02015, PI18/00337 , PI18/00330
6 · The paper itself

Abstract

Exosomes are lipid bilayer particles released from cells into their surrounding environment. These vesicles are mediators of near and long-distance intercellular communication and affect various aspects of cell biology. In addition to their biological function, they play an increasingly important role both in diagnosis and as therapeutic agents. In this paper, we review recent literature related to the molecular composition of exosomes, paying special attention to their role in pathogenesis, along with their application as biomarkers and as therapeutic tools. In this context, we analyze the potential use of exosomes in biomedicine, as well as the limitations that preclude their wider application.

Indexed as

cancer pathogenesisdiagnosticsexosomesmolecular compositiontherapeutics

Identifiers

PMID33396739
PMCPMC7795854

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.