Evidence map›Paper›PMID 33396708›Full record

ArticleInternational journal of molecular sciences2020

A Very Bright Far-Red Bioluminescence Emitting Combination Based on Engineered Railroad Worm Luciferase and 6'-Amino-Analogs for Bioimaging Purposes.

Vadim R Viviani, Vanessa R Bevilaqua, Daniel R de Souza, Gabriel F Pelentir, Michio Kakiuchi, Takashi Hirano

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Glowing wonders: exploring the diversity and ecological significance of bioluminescent organisms in Brazil.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2024
    Review
  3. Article
  4. Article
  5. Article
  6. How to Select Firefly Luciferin Analogues for In Vivo Imaging.International journal of molecular sciences · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Vadim R VivianiGraduate Program of Evolutive Genetics and Molecular Biology, Federal University of São Carlos (UFSCar), 18052-780 São Carlos, São Paulo, Brazil.
Vanessa R BevilaquaGraduate Program of Evolutive Genetics and Molecular Biology, Federal University of São Carlos (UFSCar), 18052-780 São Carlos, São Paulo, Brazil.ORCID 0000-0002-7013-0463
Daniel R de SouzaGraduate Program of Biotechnology and Environmental Monitoring, Federal University of São Carlos (UFSCar), 18119-001 Sorocaba, São Paulo, Brazil.
Gabriel F PelentirDepartment of Physics, Chemistry and Mathematics, Federal University of São Carlos (UFSCar), 18052-780 São Carlos, São Paulo, Brazil.
Michio KakiuchiDepartment of Engineering Science, Graduate School of Informatics and Engineering, The University of Electro-Communications, Chofu, Tokyo 182-8585, Japan.
Takashi HiranoDepartment of Engineering Science, Graduate School of Informatics and Engineering, The University of Electro-Communications, Chofu, Tokyo 182-8585, Japan.
Universidade Federal de São Carlos · BRUniversity of Electro-Communications · JP

Funding

CNPq 401.862/2016-1Fundação de Amparo a Pesquisa do Estado de São Paulo 2010/05426-8
6 · The paper itself

Abstract

Beetle luciferases produce bioluminescence (BL) colors ranging from green to red, having been extensively used for many bioanalytical purposes, including bioimaging of pathogen infections and metastasis proliferation in living animal models and cell culture. For bioimaging purposes in mammalian tissues, red bioluminescence is preferred, due to the lower self-absorption of light at longer wavelengths by hemoglobin, myoglobin and melanin. Red bioluminescence is naturally produced only by

Indexed as

LightLuminescent AgentsLuminescent MeasurementsMolecular ImagingAmino Acid SubstitutionAnimalsEnzyme StabilityFirefly LuciferinKineticsLuciferasesMutagenesis, Site-DirectedMutationSpectrum AnalysisStructure-Activity RelationshipThermodynamicsFirefly LuciferinLuciferasesLuminescent AgentsbioimagingbiophotonicsFar-Red bioluminescenceluciferin amino-analogsNIR bioluminescence

Identifiers

PMID33396708
PMCPMC7794784
OpenAlexW3114517846

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.