Evidence map›Paper›PMID 33396653›Full record

ArticleDiagnostics (Basel, Switzerland)2020

Synovial Tissue Proteins and Patient-Specific Variables as Predictive Factors for Temporomandibular Joint Surgery.

Mattias Ulmner, Rachael Sugars, Aron Naimi-Akbar, Nikolce Tudzarovski, Carina Kruger-Weiner, Bodil Lund

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Diagnostics (Basel, Switzerland), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06782165 (Long-term Follow up of TMJ Surgery and Evaluation of the 6-month Control as a Prognostic Marker.), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06782165 recruitingnot on this mapstarted 2025, after this paper: background citation

Long-term Follow up of TMJ Surgery and Evaluation of the 6-month Control as a Prognostic Marker.

Typeobservational_patient_registrySponsorKarolinska InstitutetRan2025 to 2027Enrolled91ConditionsTemporomandibular Disorders (TMD), Temporomandibular Joint Disc Displacement, With Reduction, Temporomandibular Joint Disc Displacement, Without ReductionArmsArthroscopy & saline irrigation alone, Discectomy
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Mattias UlmnerUnit of Cranio- and Maxillofacial Surgery, Karolinska University Hospital, 171 76 Stockholm, Sweden.ORCID 0000-0002-9429-1771
Rachael SugarsDepartment of Dental Medicine, Karolinska Institutet, 141 04 Huddinge, Sweden.ORCID 0000-0003-4843-6260
Aron Naimi-AkbarDepartment of Dental Medicine, Karolinska Institutet, 141 04 Huddinge, Sweden.ORCID 0000-0002-5248-9202
Nikolce TudzarovskiDepartment of Dental Medicine, Karolinska Institutet, 141 04 Huddinge, Sweden.
Carina Kruger-WeinerDepartment of Dental Medicine, Karolinska Institutet, 141 04 Huddinge, Sweden.
Bodil LundDepartment of Dental Medicine, Karolinska Institutet, 141 04 Huddinge, Sweden.
Karolinska Institutet · SEHaukeland University Hospital · NOKarolinska University Hospital · SEMalmö University · SE

Funding

Haukeland Universitetssjukehus -Karolinska Institutet -Swedish Dental Society -Universitetet i Bergen -
6 · The paper itself

Abstract

Our knowledge of synovial tissues in patients that are scheduled for surgery as a result of temporomandibular joint (TMJ) disorders is limited. Characterising the protein profile, as well as mapping clinical preoperative variables, might increase our understanding of pathogenesis and forecast surgical outcome. A cohort of 100 patients with either disc displacement, osteoarthritis, or chronic inflammatory arthritis (CIA) was prospectively investigated for a set of preoperative clinical variables. During surgery, a synovial tissue biopsy was sampled and analysed via multi-analytic profiling. The surgical outcome was classified according to a predefined set of outcome criteria six months postoperatively. Higher concentrations of interleukin 8 (

Indexed as

biomarkercytokineinterleukinlumicanmatrix metalloproteinasessurgerysynovial tissuesynovitistemporomandibular jointtissue inhibitor of metalloproteinases

Identifiers

PMID33396653
PMCPMC7824237
OpenAlexW3114279715

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.