Evidence map›Paper›PMID 33396610›Full record

ArticleInternational journal of molecular sciences2020

Linear Copolymers Based on Choline Ionic Liquid Carrying Anti-Tuberculosis Drugs: Influence of Anion Type on Physicochemical Properties and Drug Release.

Katarzyna Niesyto, Dorota Neugebauer

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  8. Self-Assembling Polymers withPharmaceuticals (Basel, Switzerland) · 2023
    Article
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Katarzyna NiesytoDepartment of Physical Chemistry and Technology of Polymers, Faculty of Chemistry, Silesian University of Technology, 44-100 Gliwice, Poland.
Dorota NeugebauerDepartment of Physical Chemistry and Technology of Polymers, Faculty of Chemistry, Silesian University of Technology, 44-100 Gliwice, Poland.ORCID 0000-0002-3802-744X

Funding

Narodowe Centrum Nauki the OPUS grant number 2017/27/B/ST5/00960the Polish Budget Funds for Scientific Research in 2020 as core funding for R&D activities in the Silesian University of Technology - funding for young scientists 04/040/BKM20/0131
6 · The paper itself

Abstract

In this study, drug nanocarriers were designed using linear copolymers with different contents of cholinium-based ionic liquid units, i.e., [2-(methacryloyloxy)ethyl]trimethylammonium chloride (TMAMA/Cl: 25, 50, and 75 mol%). The amphiphilicity of the copolymers was evaluated on the basis of their critical micelle concentration (CMC = 0.055-0.079 mg/mL), and their hydrophilicities were determined by water contact angles (WCA = 17°-46°). The chloride anions in the polymer chain were involved in ionic exchange reactions to introduce pharmaceutical anions, i.e.,

Indexed as

Aminosalicylic AcidAnionsAntitubercular AgentsCholineClavulanic AcidDrug CarriersDrug Delivery SystemsDrug LiberationFusidic AcidHydrophobic and Hydrophilic InteractionsIonic LiquidsMicellesPiperacillinPolymersProton Magnetic Resonance SpectroscopySpectrophotometryAminosalicylic AcidAnionsAntitubercular AgentsCholineClavulanic AcidDrug CarriersFusidic AcidIonic LiquidsMicellesPiperacillinPolymersanion exchangeantibacterial activitycholinepolymer carriers

Identifiers

PMID33396610
PMCPMC7795545

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.