Evidence map›Paper›PMID 33396584›Full record

ReviewViruses2020

Markers Associated with COVID-19 Susceptibility, Resistance, and Severity.

Aisha D Fakhroo, Asmaa A Al Thani, Hadi M Yassine

Abstract readReview
In one paragraph

Review in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Observational
  2. Article
  3. Article
  4. ERC-BiP Functional Protein Pathway for Assessing Endoplasmic Reticulum Stress Induced by SARS-CoV-2 Replication after Cell Invasion.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2023
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Observational
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Seroprevalence of SARS-CoV-2 Antibodies in Adults and Healthcare Workers in Southern Italy.International journal of environmental research and public health · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Aisha D FakhrooResearch and Development Department, Barzan Holdings, Doha 7178, Qatar.
Asmaa A Al ThaniBiomedical Research Center, Qatar University, Doha 2713, Qatar.
Hadi M YassineBiomedical Research Center, Qatar University, Doha 2713, Qatar.ORCID 0000-0001-7592-2788

Funding

Qatar University QUHI-BRC-20/21-1
6 · The paper itself

Abstract

In December 2019, the latest member of the coronavirus family, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in Wuhan, China, leading to the outbreak of an unusual viral pneumonia known as coronavirus disease 2019 (COVID-19). COVID-19 was then declared as a pandemic in March 2020 by the World Health Organization (WHO). The initial mortality rate of COVID-19 declared by WHO was 2%; however, this rate has increased to 3.4% as of 3 March 2020. People of all ages can be infected with SARS-CoV-2, but those aged 60 or above and those with underlying medical conditions are more prone to develop severe symptoms that may lead to death. Patients with severe infection usually experience a hyper pro-inflammatory immune reaction (i.e., cytokine storm) causing acute respiratory distress syndrome (ARDS), which has been shown to be the leading cause of death in COVID-19 patients. However, the factors associated with COVID-19 susceptibility, resistance and severity remain poorly understood. In this review, we thoroughly explore the correlation between various host, viral and environmental markers, and SARS-CoV-2 in terms of susceptibility and severity.

Indexed as

COVID-19Disease ResistanceDisease SusceptibilitySeverity of Illness IndexAngiotensin-Converting Enzyme 2Blood Group AntigensDisease OutbreaksEnvironmentHost-Pathogen InteractionsHumansMetabolomeMicrobiotaMiddle AgedRisk FactorsSARS-CoV-2VitaminsACE2 protein, humanAngiotensin-Converting Enzyme 2Blood Group AntigensVitaminsCOVID-19pathogenesisresistanceSARSsusceptibility

Identifiers

PMID33396584
PMCPMC7823574

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.