Evidence map›Paper›PMID 33396568›Full record

ArticleGenes2020

CRISPR/Cas9 Induced Somatic Recombination at the

Ilan Ben Shlush, Aviva Samach, Cathy Melamed-Bessudo, Daniela Ben-Tov, Tal Dahan-Meir, Shdema Filler-Hayut, Avraham A Levy

Open access · goldAbstract read
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 43 citations in OpenAlex.

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  12. Exploring impact of recombination landscapes on breeding outcomes.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Review
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  18. In-Depth Characterization ofFrontiers in plant science · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ilan Ben ShlushDepartment of Plant and Environmental Sciences, The Weizmann Institute of Science, Rehovot 7610001, Israel.
Aviva SamachDepartment of Plant and Environmental Sciences, The Weizmann Institute of Science, Rehovot 7610001, Israel.
Cathy Melamed-BessudoDepartment of Plant and Environmental Sciences, The Weizmann Institute of Science, Rehovot 7610001, Israel.
Daniela Ben-TovDepartment of Plant and Environmental Sciences, The Weizmann Institute of Science, Rehovot 7610001, Israel.
Tal Dahan-MeirDepartment of Plant and Environmental Sciences, The Weizmann Institute of Science, Rehovot 7610001, Israel.
Shdema Filler-HayutDepartment of Plant and Environmental Sciences, The Weizmann Institute of Science, Rehovot 7610001, Israel.
Avraham A LevyDepartment of Plant and Environmental Sciences, The Weizmann Institute of Science, Rehovot 7610001, Israel.
Weizmann Institute of Science · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Homologous recombination (HR) in somatic cells is not as well understood as meiotic recombination and is thought to be rare. In a previous study, we showed that Inter-Homologous Somatic Recombination (IHSR) can be achieved by targeted induction of DNA double-strand breaks (DSBs). Here, we designed a novel IHSR assay to investigate this phenomenon in greater depth. We utilized F

Indexed as

DNA End-Joining RepairGenome, PlantRecombinational DNA RepairAllelesBiological AssayCarotenoidsCRISPR-Cas SystemsCrosses, GeneticDNA Breaks, Double-StrandedDNA, PlantGene EditingGenetic LociPlant BreedingSolanum lycopersicumCarotenoidsDNA, PlantCRISPR/Cas9DNA double-strand break repairhomologous recombinationinter homologous somatic recombinationtargeted crossovertargeted gene conversiontomato

Identifiers

PMID33396568
PMCPMC7824628
OpenAlexW3113616191

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.