Evidence map›Paper›PMID 33396537›Full record

ReviewNutrients2020

The Role of Diet in the Pathogenesis and Management of Inflammatory Bowel Disease: A Review.

Gabrielle Wark, Dorit Samocha-Bonet, Simon Ghaly, Mark Danta

Open access · goldAbstract readReview
In one paragraph

Review in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 3 pooled it
13.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 3 syntheses or guidelines pooled it, 118 citations in OpenAlex.

  1. Mediterranean diet in treatment of inflammatory bowel disease: A systematic review and meta-analysis.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
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  18. Dietary Trends in Crohn's Disease: A Comparison with Healthy Controls.Current research in complementary & alternative medicine · 2025
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  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Gabrielle WarkSt Vincent's Clinical School, UNSW, Sydney 2052, Australia.
Dorit Samocha-BonetSt Vincent's Clinical School, UNSW, Sydney 2052, Australia.ORCID 0000-0001-9422-7852
Simon GhalySt Vincent's Clinical School, UNSW, Sydney 2052, Australia.ORCID 0000-0003-2489-6430
Mark DantaSt Vincent's Clinical School, UNSW, Sydney 2052, Australia.
UNSW Sydney · AUGarvan Institute of Medical Research · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inflammatory bowel diseases, which include ulcerative colitis and Crohn's disease, are chronic relapsing and remitting inflammatory diseases of the gastrointestinal tract that are increasing in prevalence and incidence globally. They are associated with significant morbidity, reduced quality of life to individual sufferers and are an increasing burden on society through direct and indirect costs. Current treatment strategies rely on immunosuppression, which, while effective, is associated with adverse events. Epidemiological evidence suggests that diet impacts the risk of developing IBD and modulates disease activity. Using diet as a therapeutic option is attractive to patients and clinicians alike due to its availability, low cost and few side effects. Diet may influence IBD risk and disease behaviour through several mechanisms. Firstly, some components of the diet influence microbiota structure and function with downstream effects on immune activity. Secondly, dietary components act to alter the structure and permeability of the mucosal barrier, and lastly dietary elements may have direct interactions with components of the immune response. This review will summarise the mechanisms of diet-microbial-immune system interaction, outline key studies examining associations between diet and IBD and evidence demonstrating the impact of diet on disease control. Finally, this review will outline current prescribed dietary therapies for active CD.

Indexed as

AnimalsBreast FeedingColitis, UlcerativeCrohn DiseaseDietary CarbohydratesDietary FatsDietary FiberDietary SugarsDisease Models, AnimalEnteral NutritionGastrointestinal MicrobiomeGlutensHost Microbial InteractionsHumansMicronutrientsNanoparticlesDietary CarbohydratesDietary FatsDietary FiberDietary SugarsGlutensMicronutrientsCrohn’s disease (CD)dietgut epitheliumgut immunitygut microbiomeinflammatory bowel disease (IBD)macronutrientsulcerative colitis (UC)

Identifiers

PMID33396537
PMCPMC7823614
OpenAlexW3116239144

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.