Evidence map›Paper›PMID 33396458›Full record

Trial reportNutrients2020

Long-Chain Polyunsaturated Fatty Acids, Homocysteine at Birth and Fatty Acid Desaturase Gene Cluster Polymorphisms are Associated with Children's Processing Speed up to Age 9 Years.

Cristina Campoy, Hatim Azaryah, Francisco J Torres-Espínola, Cristina Martínez-Zaldívar, José Antonio García-Santos, Hans Demmelmair, Gudrun Haile, Eszter Györei, María Del Carmen Ramírez-Tortosa, Eva Reischl and 6 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Investigation ofFrontiers in genetics · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 5 countries.

Cristina CampoyEURISTIKOS Excellence Centre for Paediatric Research, Biomedical Research Centre, University of Granada, 180016 Granada, Spain.ORCID 0000-0002-9860-6785
Hatim AzaryahEURISTIKOS Excellence Centre for Paediatric Research, Biomedical Research Centre, University of Granada, 180016 Granada, Spain.
Francisco J Torres-EspínolaEURISTIKOS Excellence Centre for Paediatric Research, Biomedical Research Centre, University of Granada, 180016 Granada, Spain.ORCID 0000-0002-4602-6834
Cristina Martínez-ZaldívarEURISTIKOS Excellence Centre for Paediatric Research, Biomedical Research Centre, University of Granada, 180016 Granada, Spain.
José Antonio García-SantosEURISTIKOS Excellence Centre for Paediatric Research, Biomedical Research Centre, University of Granada, 180016 Granada, Spain.
Hans DemmelmairLudwig-Maximilians-Universität München, Dept, Paediatrics, Dr. von Hauner Children's Hospital, University of Munich Hospitals, 80337 Munich, Germany.ORCID 0000-0001-7812-5178
Gudrun HaileLudwig-Maximilians-Universität München, Dept, Paediatrics, Dr. von Hauner Children's Hospital, University of Munich Hospitals, 80337 Munich, Germany.
Eszter GyöreiDepartment of Paediatrics, University of Pécs, 7623 Pécs, József Attila u. 7, Pécs 7623, Hungary.
María Del Carmen Ramírez-TortosaDepartment of Biochemistry and Molecular Biology II, Institute of Nutrition and Food Technology "José Mataix Verdú", Biomedical Research Center, University of Granada, Avda del Conocimiento s/n., 18100 Armilla, Granada, Spain.ORCID 0000-0002-7999-0881
Eva ReischlHelmholtz Zentrum Munchen, Research Unit of Molecular Epidemiology, D-85764 Neuherberg, Germany.
Peter RzehakLudwig-Maximilians-Universität München, Dept, Paediatrics, Dr. von Hauner Children's Hospital, University of Munich Hospitals, 80337 Munich, Germany.ORCID 0000-0001-6871-7567
Anne M MolloySchool of Medicine, Trinity College, 152-160 Pearse Street, Dublin 2, Ireland.ORCID 0000-0002-1688-9049
Tamas DécsiDepartment of Paediatrics, University of Pécs, 7623 Pécs, József Attila u. 7, Pécs 7623, Hungary.
Juan de Dios LunaDepartment of Biostatistics, School of Medicine, University of Granada,18016 Granada, Spain.
Berthold KoletzkoLudwig-Maximilians-Universität München, Dept, Paediatrics, Dr. von Hauner Children's Hospital, University of Munich Hospitals, 80337 Munich, Germany.ORCID 0000-0002-5345-7165
Miguel Pérez-GarcíaMind, Brain and Behaviour International Research Centre (CIMCYC), University of Granada, 18011 Granada, Spain.ORCID 0000-0003-4775-7556
Universidad de Granada · ESLudwig-Maximilians-Universität München · DEUniversity of Pecs · HUHelmholtz Zentrum München · DETrinity College Dublin · IE

Funding

6th Framework Program, EARNEST Project 007036Commission of the European Community's 7th Framework Program (FP7/2008-2013) 212652Commission of the European Community within the 5th Framework Program (NUHEAL Project) QLK1-CT-1999-00888
6 · The paper itself

Abstract

Both pre- and early postnatal supplementation with docosahexaenoic acid (DHA), arachidonic acid (AA) and folate have been related to neural development, but their long-term effects on later neural function remain unclear. We evaluated the long-term effects of maternal prenatal supplementation with fish-oil (FO), 5-methyltetrahydrofolate (5-MTHF), placebo or FO + 5-MTHF, as well as the role of fatty acid desaturase (

Indexed as

Dietary SupplementsAdultBrainChildChild DevelopmentCognitionDelta-5 Fatty Acid DesaturaseDocosahexaenoic AcidsFatty Acid DesaturasesFemaleFetal BloodFollow-Up StudiesHomocysteineHumansInfant, NewbornInfant Nutritional Physiological Phenomena5-methyltetrahydrofolateDelta-5 Fatty Acid DesaturaseDocosahexaenoic AcidsFADS1 protein, humanFatty Acid DesaturasesHomocysteineMethylenetetrahydrofolate Reductase (NADPH2)MTHFR protein, humanTetrahydrofolateschildrenFADS genefolatelong-chain polyunsaturated fatty acidsneurodevelopmentprenatal supplementationprocessing speed

Identifiers

PMID33396458
PMCPMC7824114
OpenAlexW3116440094

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.