Evidence map›Paper›PMID 33396418›Full record

ArticleGenes2020

Progressive External Ophthalmoplegia in Polish Patients-From Clinical Evaluation to Genetic Confirmation.

Biruta Kierdaszuk, Magdalena Kaliszewska, Joanna Rusecka, Joanna Kosińska, Ewa Bartnik, Katarzyna Tońska, Anna M Kamińska, Anna Kostera-Pruszczyk

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Biruta KierdaszukDepartment of Neurology, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.ORCID 0000-0002-8072-2497
Magdalena KaliszewskaInstitute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Pawinskiego 5a, 02-106 Warsaw, Poland.
Joanna RuseckaInstitute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Pawinskiego 5a, 02-106 Warsaw, Poland.
Joanna KosińskaDepartment of Medical Genetics, Medical University of Warsaw, Pawinskiego 3c, 02-106 Warsaw, Poland.
Ewa BartnikInstitute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Pawinskiego 5a, 02-106 Warsaw, Poland.ORCID 0000-0003-0489-7102
Katarzyna TońskaInstitute of Genetics and Biotechnology, Faculty of Biology, University of Warsaw, Pawinskiego 5a, 02-106 Warsaw, Poland.
Anna M KamińskaDepartment of Neurology, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
Anna Kostera-PruszczykDepartment of Neurology, Medical University of Warsaw, Banacha 1a, 02-097 Warsaw, Poland.
Medical University of Warsaw · PLUniversity of Warsaw · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mitochondrial encephalomyopathies comprise a group of heterogeneous disorders resulting from impaired oxidative phosphorylation (OxPhos). Among a variety of symptoms progressive external ophthalmoplegia (PEO) seems to be the most common. The aim of this study is to present clinical and genetic characteristics of Polish patients with PEO. Clinical, electrophysiological, neuroradiological, and morphological data of 84 patients were analyzed. Genetic studies of mitochondrial DNA (mtDNA) were performed in all patients. Among nuclear DNA (nDNA) genes

Indexed as

AdolescentAdultAgedCerebellumCerebrumChildDiagnosis, DifferentialDNA HelicasesDNA, MitochondrialDNA Polymerase gammaFemaleGene ExpressionHumansKearns-Sayre SyndromeMaleMiddle AgedDNA HelicasesDNA, MitochondrialDNA Polymerase gammaMitochondrial ProteinsPOLG protein, humanRibonuclease Hribonuclease HITWNK protein, humanmitochondrial disordersmitochondrial DNA deletionsmultiple mitochondrial DNA deletionsmuscle biopsyPOLG geneprogressive external ophthalmoplegiaRNASEH1 geneTWNK gene

Identifiers

PMID33396418
PMCPMC7824435
OpenAlexW3114744785

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.