SynthesisInternational journal of molecular sciences2020
Effect of Cavity Disinfectants on Dentin Bond Strength and Clinical Success of Composite Restorations-A Systematic Review of In Vitro, In Situ and Clinical Studies.
Synthesis in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 3 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Impact of bonding protocols and physical-mechanical properties of composite on durability and failure rate of fixed orthodontic retainers: a systematic review of laboratory studies.BMC oral health · 2025Pooled it
- Which Zirconia Surface-cleaning Strategy Improves Adhesion of Resin Composite Cement after Saliva Contamination? A Systematic Review and Meta-Analysis.The journal of adhesive dentistry · 2022Pooled it
- Effect of Cavity Disinfectants on Adhesion to Primary Teeth-A Systematic Review.International journal of molecular sciences · 2021Pooled it
- Comparative Evaluation of Antimicrobial Activity of Dentin Disinfection Protocols Against MRSA andJournal of functional biomaterials · 2026Article
- Effect of Bond Strength of Chitosan Containing Cavity Disinfectant on Deep or Superficial Dentin.Biomimetics (Basel, Switzerland) · 2026Article
- Effects and Properties of Deproteinizing Methods in Dentin: A Comprehensive Narrative Review.Journal of functional biomaterials · 2026Review
- Investigation of the effect of using cavity disinfectant on microleakage in composite restorations by micro-CT analysis.European oral research · 2026Article
- The antibacterial effect of chlorohexidine, Er:YAG laser and diode laser 980 nm as dental cavity disinfectants of dentine: an in vitro study.European journal of medical research · 2025Article
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- Effect of Dentin Contamination with Hemostatic Agents and Cleaning Techniques on Bonding with Self-Adhesive Resin Cement.Medical science monitor : international medical journal of experimental and clinical research · 2024Article
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- Evaluation of different decontamination procedures on bond strength to sound and caries affected dentin using "no-wait" universal adhesive.BMC oral health · 2023Article
- Effect of Antibacterial Agents on Dentin Bond Strength of Bioactive Restorative Materials.Polymers · 2023Article
- Postoperative Pain of Pediatric Patients Undergoing Dental Treatment under General Anesthesia Visiting a General Hospital: A Cross-Sectional Study.Children (Basel, Switzerland) · 2023Article
- The comparative evaluation of the effects of quercetin, α-tocopherol, and chlorhexidine dentin pretreatments on the durability of universal adhesives.Clinical and experimental dental research · 2022Article
- Effect of Different Cavity Disinfectants on Adhesion to Dentin of Permanent Teeth.Journal of functional biomaterials · 2022Article
- The effects of amalgam contamination and different surface modifications on microleakage of dentin bonded to bulk fill composite when using different adhesive protocols.BMC oral health · 2022Article
- Effect of dentin surface pretreatment with four conditioning agents on micro-shear bond strength of a self-adhesive cement.Journal of clinical and experimental dentistry · 2022Article
- Photoinactivation of multispecies cariogenic biofilm mediated by aluminum phthalocyanine chloride encapsulated in chitosan nanoparticles.Lasers in medical science · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cavity disinfection becomes an important step before a dental restorative procedure. The disinfection can be obtained cleaning the dental cavity with antimicrobial agents before the use of adhesive systems. The aim of this study was to conduct a systematic review on the effect of different cavity disinfectants on restorations' adhesion and clinical success. A search was carried out through the Cochrane Library, PubMed, and Web of Science. In vitro and in situ studies reporting results on dentin bond strength tests, and clinical studies published until August 2020, in English, Spanish and Portuguese were included. The methodological quality assessment of the clinical studies was carried out using the Revised Cochrane risk-of-bias tool. Chlorhexidine could preserve adhesion to dentin. EDTA and ethanol had positive results that should be further confirmed. Given the significant lack of scientific evidence, the use of lasers, fluoridated agents, sodium hypochlorite, or other products as cavity disinfectants should be avoided. Chlorhexidine is a safe option for cavity disinfection with adequate preservation of adhesion to dentin. Moreover, future researches should be focused on the efficacy of these disinfectants against cariogenic bacteria and their best application methods.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.