Evidence map›Paper›PMID 33396318›Full record

Observational studyNutrients2020

Low Dietary Magnesium and Overweight/Obesity in a Mediterranean Population: A Detrimental Synergy for the Development of Hypertension. The SUN Project.

Ligia J Dominguez, Alfredo Gea, Liz Ruiz-Estigarribia, Carmen Sayón-Orea, Ujue Fresán, Mario Barbagallo, Miguel Ruiz-Canela, Miguel A Martínez-González

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Associations between dietary magnesium intake and hypertension, diabetes, and hyperlipidemia.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Serum Magnesium is Inversely Associated with Body Composition and Metabolic Syndrome.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Ligia J DominguezGeriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, 90127 Palermo, Italy.
Alfredo GeaDepartment of Preventive Medicine and Public Health, University of Navarra-IDISNA, 31008 Pamplona, Spain.
Liz Ruiz-EstigarribiaDepartment of Preventive Medicine and Public Health, University of Navarra-IDISNA, 31008 Pamplona, Spain.
Carmen Sayón-OreaDepartment of Preventive Medicine and Public Health, University of Navarra-IDISNA, 31008 Pamplona, Spain.
Ujue FresáneHealth Group, ISGlobal, 08036 Barcelona, Spain.ORCID 0000-0001-8140-4338
Mario BarbagalloGeriatric Unit, Department of Internal Medicine and Geriatrics, University of Palermo, 90127 Palermo, Italy.ORCID 0000-0002-1349-6530
Miguel Ruiz-CanelaDepartment of Preventive Medicine and Public Health, University of Navarra-IDISNA, 31008 Pamplona, Spain.ORCID 0000-0002-7684-2787
Miguel A Martínez-GonzálezDepartment of Preventive Medicine and Public Health, University of Navarra-IDISNA, 31008 Pamplona, Spain.ORCID 0000-0002-3917-9808
Instituto de Salud Carlos III · ESUniversity of Palermo · ITBarcelona Institute for Global Health · ESHarvard University · US

Funding

European Regional Development Fund RD 06/0045
6 · The paper itself

Abstract

Hypertension is the strongest independent modifiable risk factor for cardiovascular disease. We aimed to investigate the association of magnesium intake with incident hypertension in a Mediterranean population, and the potential modification of this association by body mass index BMI. We assessed 14,057 participants of the SUN (Seguimiento Universidad de Navarra) prospective cohort (67.0% women) initially free of hypertension. At baseline, a validated 136-item food frequency questionnaire was administered. We used Cox models adjusted for multiple socio-demographic, anthropometric, and lifestyle factors, and prevalent conditions present at baseline. Among a mean 9.6 years of follow-up we observed 1406 incident cases of medically diagnosed hypertension. An inverse association in multivariable-adjusted models was observed for progressively higher magnesium intake up to 500 mg/d vs. intake < 200 mg/d, which was greater among those with a BMI > 27 kg/m

Indexed as

AdultDiet, MediterraneanDiet SurveysFeeding BehaviorFemaleFollow-Up StudiesHumansHypertensionIncidenceLongitudinal StudiesMagnesiumMaleMiddle AgedObesityOverweightProspective StudiesMagnesiumcohort studiesdiethypertensionmagnesiumobesityoverweight

Identifiers

PMID33396318
PMCPMC7824180
OpenAlexW3117652555

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.