Evidence map›Paper›PMID 33396306›Full record

ReviewJournal of clinical medicine2020

Therapeutics Development for Pseudoxanthoma Elasticum and Related Ectopic Mineralization Disorders: Update 2020.

Hongbin Luo, Qiaoli Li, Yi Cao, Jouni Uitto

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Lax skin and blurring of vision- A case report of pseudoxanthoma elasticum.Journal of family medicine and primary care · 2022
    Article
  13. Article
  14. [Pseudoxanthoma elasticum: the dermatologist as a guide].Dermatologie (Heidelberg, Germany) · 2022
    Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Hongbin LuoDepartment of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College and the PXE International Center for Excellence in Research and Clinical Care, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Qiaoli LiDepartment of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College and the PXE International Center for Excellence in Research and Clinical Care, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Yi CaoDepartment of Dermatology, The First Affiliated Hospital of Zhejiang Chinese Medical University, Hangzhou 310006, China.
Jouni UittoDepartment of Dermatology and Cutaneous Biology, Sidney Kimmel Medical College and the PXE International Center for Excellence in Research and Clinical Care, Thomas Jefferson University, Philadelphia, PA 19107, USA.
Thomas Jefferson University · USZhejiang Chinese Medical University · CN

Funding

BIOCHEMISTRY AND MORPHOLOGY OF CONNECTIVE TISSUESR01AR028450 · NIAMS · THOMAS JEFFERSON UNIVERSITY · PI UITTO, JOUNI · 1986 to 2019
$6.5M
Model Systems for PXER01AR055225 · NIAMS · THOMAS JEFFERSON UNIVERSITY · PI UITTO, JOUNI · 2008 to 2017
$3.2M
Novel Treatments for PXER01AR072695 · NIAMS · THOMAS JEFFERSON UNIVERSITY · PI LI, QIAOLI, VAN DE WETERING, KOEN · 2018 to 2022
$1.7M
Modifier Genes for Ectopic MineralizationK01AR064766 · NIAMS · THOMAS JEFFERSON UNIVERSITY · PI LI, QIAOLI · 2014 to 2018
$634k
NIAMS NIH HHS K01 AR064766NIAMS NIH HHS R01 AR028450NIAMS NIH HHS R01 AR055225NIAMS NIH HHS R01 AR072695
6 · The paper itself

Abstract

Pseudoxanthoma elasticum (PXE), the prototype of heritable ectopic mineralization disorders, manifests with deposition of calcium hydroxyapatite crystals in the skin, eyes and arterial blood vessels. This autosomal recessive disorder, due to mutations in

Indexed as

arterial calcification due to CD73 deficiencyectopic mineralization disordersgeneralized arterial calcification of infancypseudoxanthoma elasticumtherapy development

Identifiers

PMID33396306
PMCPMC7795895
OpenAlexW3115141084

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.