Evidence map›Paper›PMID 33396240›Full record

ReviewCells2020

Circulating Non-Coding RNAs in Head and Neck Cancer: Roles in Diagnosis, Prognosis, and Therapy Monitoring.

Araceli Diez-Fraile, Joke De Ceulaer, Charlotte Derpoorter, Christophe Spaas, Tom De Backer, Philippe Lamoral, Johan Abeloos, Tim Lammens

Open access · goldAbstract readReview
In one paragraph

Review in Cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Araceli Diez-FraileDivision of Oral and Maxillofacial Surgery, Department of Surgery, AZ Sint-Jan Brugge-Oostende A.V., 8000 Bruges, Belgium.
Joke De CeulaerDivision of Oral and Maxillofacial Surgery, Department of Surgery, AZ Sint-Jan Brugge-Oostende A.V., 8000 Bruges, Belgium.
Charlotte DerpoorterDepartment of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, 9000 Ghent, Belgium.
Christophe SpaasDivision of Oral and Maxillofacial Surgery, Department of Surgery, AZ Sint-Jan Brugge-Oostende A.V., 8000 Bruges, Belgium.
Tom De BackerDivision of Oral and Maxillofacial Surgery, Department of Surgery, AZ Sint-Jan Brugge-Oostende A.V., 8000 Bruges, Belgium.
Philippe LamoralDivision of Oral and Maxillofacial Surgery, Department of Surgery, AZ Sint-Jan Brugge-Oostende A.V., 8000 Bruges, Belgium.
Johan AbeloosDivision of Oral and Maxillofacial Surgery, Department of Surgery, AZ Sint-Jan Brugge-Oostende A.V., 8000 Bruges, Belgium.
Tim LammensDepartment of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, 9000 Ghent, Belgium.ORCID 0000-0001-8733-4027
AZ Sint-Jan · BEGhent University Hospital · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Head and neck cancer (HNC), the seventh most common form of cancer worldwide, is a group of epithelial malignancies affecting sites in the upper aerodigestive tract. The 5-year overall survival for patients with HNC has stayed around 40-50% for decades, with mortality being attributable mainly to late diagnosis and recurrence. Recently, non-coding RNAs, including tRNA halves, YRNA fragments, microRNAs (miRNAs), and long non-coding RNAs (lncRNAs), have been identified in the blood and saliva of patients diagnosed with HNC. These observations have recently fueled the study of their potential use in early detection, diagnosis, and risk assessment. The present review focuses on recent insights and the potential impact that circulating non-coding RNA evaluation may have on clinical decision-making in the management of HNC.

Indexed as

Biomarkers, TumorFemaleGene Expression Regulation, NeoplasticHead and Neck NeoplasmsHumansLiquid BiopsyMaleNeoplasm Recurrence, LocalPrognosisRNA, UntranslatedSalivaBiomarkers, TumorRNA, Untranslatedbiomarkerscirculating non-coding RNAhead and neck cancerliquid biopsy

Identifiers

PMID33396240
PMCPMC7823329
OpenAlexW3115100305

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.