Evidence map›Paper›PMID 33396232›Full record

ArticleBrain sciences2020

Analysis of NOS Gene Polymorphisms in Relation to Cluster Headache and Predisposing Factors in Sweden.

Caroline Ran, Julia M Michalska, Carmen Fourier, Christina Sjöstrand, Elisabet Waldenlind, Anna Steinberg, Andrea C Belin

Open access · goldAbstract read
In one paragraph

Article in Brain sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Caroline RanDepartment of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0003-0239-9871
Julia M MichalskaDepartment of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0003-3862-1235
Carmen FourierDepartment of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0001-6618-8948
Christina SjöstrandDepartment of Clinical Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.
Elisabet WaldenlindDepartment of Clinical Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.
Anna SteinbergDepartment of Clinical Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.
Andrea C BelinDepartment of Neuroscience, Karolinska Institutet, 171 77 Stockholm, Sweden.ORCID 0000-0001-6668-3172
Karolinska Institutet · SEKarolinska University Hospital · SE

Funding

Karolinska Institutet 2018-01738Märta Lundqvists Stiftelse 2019Swedish Brain Foundation and Mellby Gård Foundation FO2018-0008, FO2019-0004Vetenskapsrådet FO2019-0004
6 · The paper itself

Abstract

Cluster headache is characterized by activation of the autonomic-trigeminal reflex. Nitric oxide can trigger headaches in patients, and nitric oxide signaling is known to be affected in cluster headache. Based on the hypothesis of nitric oxide being involved in cluster headache pathophysiology we investigated nitric oxide synthases as potential candidate genes for cluster headache. We analyzed eight variants in the three forms of nitric oxide synthase (

Indexed as

haplotypeneurovascularnitric oxidenitric oxide synthasesmoking

Identifiers

PMID33396232
PMCPMC7824326
OpenAlexW3117184065

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.