Evidence map›Paper›PMID 33395970›Full record

ArticleNeuroImage. Clinical2020

Examining the relationship between measures of autistic traits and neural synchrony during movies in children with and without autism.

K M Lyons, R A Stevenson, A M Owen, B Stojanoski

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NeuroImage. Clinical, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 2 pooled it
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

K M LyonsThe Brain and Mind Institute, Western University, London, ON N6A 5B7, Canada; The Department of Psychology, Western University, London, ON N6A 5B7, Canada.
R A StevensonThe Brain and Mind Institute, Western University, London, ON N6A 5B7, Canada; The Department of Psychology, Western University, London, ON N6A 5B7, Canada.
A M OwenThe Brain and Mind Institute, Western University, London, ON N6A 5B7, Canada; The Department of Psychology, Western University, London, ON N6A 5B7, Canada; The Department of Physiology and Pharmacology, Western University, London, ON N6A 5B7, Canada.
B StojanoskiThe Brain and Mind Institute, Western University, London, ON N6A 5B7, Canada; The Department of Psychology, Western University, London, ON N6A 5B7, Canada. Electronic address: bstojan@uwo.ca.
Western University · CA

Funding

CIHR 408004
6 · The paper itself

Abstract

Children who have been diagnosed with autism spectrum disorder (ASD) often show a marked deficit in measures of social cognition. In autistic adults, measures of social cognition have been shown to relate to differences in brain synchronization (as measured by fMRI) when individuals are processing naturalistic stimuli, such as movies. However, whether children who differ in their degree of autistic traits, with or without a diagnosis of ASD, differ in their neural responses to movies has not yet been investigated. In the current study, neural synchrony, measured using fMRI, was examined in three groups of children aged 7 to 12, who differed with respect to scores on a measure of autistic traits associated with social impairment and whether or not they had been diagnosed with ASD. While watching the movie 'Despicable Me', those diagnosed with ASD had significantly less neural synchrony in areas that have been previously shown to be associated with social cognition (e.g. areas related to 'theory of mind'), and plot following (e.g. the lateral prefrontal cortex), than those who did not have an ASD diagnosis. In contrast, two groups who differed in their degree of autistic traits, but did not have a diagnosis of ASD, showed no significant differences in neural synchrony across the whole brain. These results shed some light on how autistic traits may contribute to an individual's conscious experience of the world, and how, for children with ASD, that experience may differ markedly from that of those without ASD.

Indexed as

Autism Spectrum DisorderAutistic DisorderAdultBrainChildHumansMagnetic Resonance ImagingMotion PicturesAutism spectrum disorderAutistic traitsDevelopmentfMRINeural synchronyTheory of mind

Identifiers

PMID33395970
PMCPMC7680702
OpenAlexW3097727933

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.