Evidence map›Paper›PMID 33395833›Full record

ArticleInternational journal of surgery case reports2020

A case report of diffuse hyperplastic gastropathy with multiple polypoid formations in a patient with pernicious anemia, Helicobacter pylori infection, hypergastrinemia and hypoalbuminaemia: Do not forget of Ménétrier's disease.

Daniel Reis Waisberg, Evandro Sobroza de Mello, Francisco Tustumi, Daniel José Szor, Amir Zeide Charruf, Felipe Emanuel Fuhro, Jaques Waisberg, André Roncon Dias

Open access · goldAbstract readCase Reports
In one paragraph

Article in International journal of surgery case reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. A rare case of Menetrier's disease-induced gastric outlet obstruction.The Kaohsiung journal of medical sciences · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Daniel Reis WaisbergDepartment of Surgery, Hospital de Clínicas Municipal José Alencar, Sao Bernardo do Campo, Brazil.
Evandro Sobroza de MelloDepartment of Pathology, Instituto do Câncer do Estado de São Paulo (ICESP), Sao Paulo, Brazil.
Francisco TustumiDepartment of Surgery, Hospital de Clínicas Municipal José Alencar, Sao Bernardo do Campo, Brazil. Electronic address: franciscotustumi@gmail.com.
Daniel José SzorDepartment of Surgery, Hospital de Clínicas Municipal José Alencar, Sao Bernardo do Campo, Brazil.
Amir Zeide CharrufDepartment of Surgery, Hospital de Clínicas Municipal José Alencar, Sao Bernardo do Campo, Brazil.
Felipe Emanuel FuhroDepartment of Surgery, Hospital de Clínicas Municipal José Alencar, Sao Bernardo do Campo, Brazil.
Jaques WaisbergDigestive and General Surgery Department, ABC Medical School (FMABC), Santo Andre, Brazil.
André Roncon DiasDepartment of Surgery, Hospital de Clínicas Municipal José Alencar, Sao Bernardo do Campo, Brazil.
Hospital de Clínicas de Porto Alegre · BRFaculdade de Medicina do ABC · BRInstituto do Câncer do Estado de São Paulo · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionMénétrier's disease is a rare condition, frequently associated with Helicobacter pylori infection, hypergastrinemia and hypoalbuminaemia. PRESENTATION OF THE CASE: A case of a 55 years-old female patient with a previous diagnosis of pernicious anemia complaining of epigastric discomfort, hyporexia, vomiting, and weight loss is reported. Endoscopy showed multiple gastric polyploid formations and Helicobacter pylori infection was detected. Laboratory tests showed elevated gastrin serum levels and presence of antibodies antiparietal cells, as well as microcytic hypochromic anemia compatible with chronic iron deficiency. Albumin serum level was slightly decreased. Full thickness biopsy performed via echoendoscopy reported gastritis cystica/polyposa profunda. Given the association of diffuse involvement of the entire stomach, the possibility of developing malignant disease and the clinical symptoms, the patient underwent laparoscopic total gastrectomy with Roux-en-Y reconstruction. The surgical specimen showed the mucosa hyperemic and swollen, with prominent gastric folds. Hyperplastic elongation of gastric foveolas associated with disappearance of oxyntic glands was compatible with Ménétrier's disease. DISCUSSION: The Ménétrier's disease diagnosis may be tricky, especially when an unusual endoscopic presentation is associated with other conditions that may mislead the diagnostic evaluation. The differential diagnoses were gastric malignancies, Zollinger-Ellison syndrome, massive gastric polyposis and gastritis cystica/polyposa profunda.

conclusionClinical, laboratory, endoscopic and histopathological findings are paramount for reaching the diagnosis of Ménétrier's disease, but it should be suspected in all cases of upper gastrointestinal symptoms and hypertrophied gastric mucosa.

Indexed as

Case reportGastrectomyHypertrophic gastritis

Identifiers

PMID33395833
PMCPMC7700994
OpenAlexW3105738816

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.