Evidence map›Paper›PMID 33395425›Full record

ArticlePLoS neglected tropical diseases2021

Epidemiological, socio-demographic and clinical features of the early phase of the COVID-19 epidemic in Ecuador.

Esteban Ortiz-Prado, Katherine Simbaña-Rivera, Lenin Gómez Barreno, Ana Maria Diaz, Alejandra Barreto, Carla Moyano, Vannesa Arcos, Eduardo Vásconez-González, Clara Paz, Fernanda Simbaña-Guaycha and 8 more

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  7. Drivers of COVID-19 infections: Perspectives of managers in the Gauteng Department of Health, South Africa.South African family practice : official journal of the South African Academy of Family Practice/Primary Care · 2025
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21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Esteban Ortiz-PradoOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito, Ecuador.ORCID 0000-0002-1895-7498
Katherine Simbaña-RiveraOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito, Ecuador.ORCID 0000-0002-8130-5361
Lenin Gómez BarrenoOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito, Ecuador.ORCID 0000-0002-4499-0304
Ana Maria DiazOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito, Ecuador.
Alejandra BarretoOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito, Ecuador.ORCID 0000-0001-7477-9721
Carla MoyanoOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito, Ecuador.
Vannesa ArcosOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito, Ecuador.
Eduardo Vásconez-GonzálezOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito, Ecuador.ORCID 0000-0003-4573-6217
Clara PazSchool of psychology, Universidad de Las Americas, Quito, Ecuador.ORCID 0000-0003-1106-9567
Fernanda Simbaña-GuaychaScientific Association of Medical Students, Universidad Central del Ecuador, Quito, Ecuador.
Martin Molestina-LuzuriagaOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito, Ecuador.
Raúl Fernández-NaranjoOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito, Ecuador.
Javier FeijooInstituto de Física La Plata, Universidad Nacional de la Plata, La Plata, Argentina.ORCID 0000-0002-0917-909X
Aquiles R Henriquez-TrujilloOne Health Research Group, Faculty of Health Science, Universidad de Las Americas, Quito, Ecuador.ORCID 0000-0002-3094-4438
Lila AdanaSchool of psychology, Universidad de Las Americas, Quito, Ecuador.ORCID 0000-0002-7011-0251
Andrés López-CortésCentro de Investigación Genética y Genómica, Facultad de Ciencias de la Salud Eugenio Espejo, Universidad UTE, Quito, Ecuador.ORCID 0000-0003-1503-1929
Isabel FletcherCentre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.ORCID 0000-0002-3175-6877
Rachel LoweCentre for Mathematical Modelling of Infectious Diseases, London School of Hygiene & Tropical Medicine, London, United Kingdom.ORCID 0000-0003-3939-7343

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The SARS-CoV-2 virus has spread rapidly around the globe. Nevertheless, there is limited information describing the characteristics and outcomes of COVID-19 patients in Latin America. We conducted a cross-sectional analysis of 9,468 confirmed COVID-19 cases reported in Ecuador. We calculated overall incidence, mortality, case fatality rates, disability adjusted life years, attack and crude mortality rates, as well as relative risk and relative odds of death, adjusted for age, sex and presence of comorbidities. A total of 9,468 positive COVID-19 cases and 474 deaths were included in the analysis. Men accounted for 55.4% (n = 5, 247) of cases and women for 44.6% (n = 4, 221). We found the presence of comorbidities, being male and older than 65 years were important determinants of mortality. Coastal regions were most affected by COVID-19, with higher mortality rates than the highlands. Fatigue was reported in 53.2% of the patients, followed by headache (43%), dry cough (41.7%), ageusia (37.1%) and anosmia (36.1%). We present an analysis of the burden of COVID-19 in Ecuador. Our findings show that men are at higher risk of dying from COVID-19 than women, and risk increases with age and the presence of comorbidities. We also found that blue-collar workers and the unemployed are at greater risk of dying. These early observations offer clinical insights for the medical community to help improve patient care and for public health officials to strengthen Ecuador's response to the outbreak.

Indexed as

Disease OutbreaksAdolescentAdultAgedAged, 80 and overAge DistributionChildChild, PreschoolCost of IllnessCOVID-19Cross-Sectional StudiesEcuadorFemaleGeographyHumansInfant

Identifiers

PMID33395425
PMCPMC7817051

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.