Evidence map›Paper›PMID 33394378›Full record

ReviewHead and neck pathology2021

Myoepithelial Carcinoma Ex Pleomorphic Adenoma of the Maxillary Sinus: A Case Report and Review of Literature.

Giovacchini Francesco, Caselli Emanuele, Monarchi Gabriele, Mitro Valeria, Sidoni Angelo, Tullio Antonio

Open access · greenAbstract readCase ReportsReview
In one paragraph

Review in Head and neck pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Giovacchini FrancescoDepartment of Maxillo-Facial Surgery, Hospital of Perugia, Sant'Andrea Delle Fratte, 06132, Perugia, Italy.
Caselli EmanueleDepartment of Experimental Medicine, Section of Anatomic Pathology and Histology, Medical School, University of Perugia, Perugia, Italy.
Monarchi GabrieleDepartment of Medicine, University of Perugia, Piazzale Gambuli 1, 06129, Perugia, Italy. gabriele.monarchi@gmail.com.ORCID http://orcid.org/0000-0001-7489-3794
Mitro ValeriaDepartment of Maxillo-Facial Surgery, Hospital of Perugia, Sant'Andrea Delle Fratte, 06132, Perugia, Italy.
Sidoni AngeloDepartment of Experimental Medicine, Section of Anatomic Pathology and Histology, Medical School, University of Perugia, Perugia, Italy.
Tullio AntonioDepartment of Surgery and Biomedical Sciences, Section of Maxillo-Facial Surgery, University of Perugia, Piazzale Gambuli 1, 06129, Perugia, Italy.
University of Perugia · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myoepithelial carcinoma ex pleomorphic adenoma is defined as a malignant epithelial neoplasm arising from a primary or recurrent benign pleomorphic adenoma. This type of tumor comprises 3.6% of all salivary gland tumors and 12% of malignant ones. Clinically, it most commonly presents as a firm mass in the parotid gland. The development of this neoplasm in the sinonasal and nasopharyngeal regions is extremely rare and only few cases are reported in the literature. The prognosis of myoepithelial carcinoma is variable. Marked cellular pleomorphism, high mitotic rate, and high proliferative activity correspond to a poor prognosis. In this article, the authors report the histopathological features of a clinical case of a 64-years-old patient with a large median maxillary neoplasm diagnosed as myoepithelial carcinoma/ex-pleomorphic adenoma. The tumor was resected and subjected to secondary reconstruction using a revascularized free fibula flap. The myoepithelial derivation of neoplastic cells was demonstrated by immunohistochemical positivity for S-100 protein (strong and diffuse), cytokeratin 14 (strong and diffuse), and GFAP (focal).

Indexed as

Adenoma, PleomorphicCarcinomaDiagnosis, DifferentialHumansMaxillary NeoplasmsMiddle AgedNeoplasm StagingParanasal Sinus NeoplasmsCraniofacial surgeryEx pleomorphic adenomaFree flapMaxillary sinusMicrovascular surgeryMyoepithelial carcinoma

Identifiers

PMID33394378
PMCPMC8633205
OpenAlexW3119602061

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.